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Comparison of Diaphragm Ultrasound and RSBI for Predicting Weaning Success in Mechanically Ventilated ICU Patients

NCT07120438 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 55

Last updated 2025-08-13

No results posted yet for this study

Summary

The goal of this observational study is to evaluate the predictive value of diaphragmatic ultrasound compared to the Rapid Shallow Breathing Index (RSBI) in determining weaning success among mechanically ventilated patients in the ICU for more than 48 hours.

The main question it aims to answer is:

Which is more effective in predicting weaning success: diaphragmatic ultrasound (including Diaphragmatic Excursion \[DE\] and Diaphragm Thickening Fraction \[DTF\]) or RSBI, in patients ventilated \>48 hours in the ICU of Dr. Sardjito General Hospital, Yogyakarta?

Participants will be adult ICU patients who are undergoing weaning from mechanical ventilation after more than 48 hours. Before extubation, each participant will undergo diaphragmatic ultrasound assessment to measure DE and DTF, along with RSBI measurement. The predictive accuracy of these parameters will be evaluated by comparing them with the actual weaning outcomes.

Secondary objectives include:

1. Assessing whether diaphragmatic ultrasound is associated with a higher weaning success rate than RSBI.
2. Evaluating the correlation between DE values and successful weaning.
3. Determining the optimal cutoff values of DE and DTF as predictors of weaning failure.
4. Analyzing the incidence of weaning failure in patients who do not meet optimal diaphragm function criteria.
5. Identifying DE and DTF thresholds that may help reduce the risk of reintubation.

Conditions

  • Ventilator Weaning
  • Mechanical Ventilation
  • Respiratory Insufficiency Requiring Mechanical Ventilation
  • Weaning From Mechanical Ventilation
  • Weaning From Mechanical Ventilation in Care Unit
  • Intensive Care Unit Patients

Sponsors & Collaborators

  • Gadjah Mada University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-31
Primary Completion
2026-01-31
Completion
2026-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07120438 on ClinicalTrials.gov