Pediatric Intravenous Contrast-Enhanced Ultrasound(CEUS) in China

Summary

The goal of this clinical trial is to evaluate the application of intravenous contrast-enhanced ultrasound examination in children with intra-abdominal diseases that require clear diagnoses. The main questions it aims to answer are:

* Is intravenous contrast-enhanced ultrasound helpful for the diagnosis of intra-abdominal diseases in children?
* What medical problems do participants have when participating in intravenous contrast-enhanced ultrasound examination?
* How can ultrasound doctors conduct intravenous contrast-enhanced ultrasound examinations in a standardized manner? Researchers will performing intravenous contrast-enhanced ultrasound examinations on participants and collecting research subjects to establish a multicenter clinical data database.

Participants will:

* Perform abdominal ultrasound examination to assess the condition.
* At least conduct one intravenous contrast-enhanced ultrasound examination. Based on the result of the contrast examination, decide whether to conduct another examination.
* Keep a diary of their symptoms and therapeutic process in 30 days.

Conditions

• Abdominal Neoplasm
• Abdominal Injury
• Ascites

Interventions

DEVICE

contrast-enhanced ultrasound examination

to evaluate the the application of contrast-enhanced ultrasound examination in children with intra-abdominal diseases that require clear diagnoses aged from 29 days to 18 years old

DRUG

SonoVue®

perform contrast enhanced ultrasound (CEUS) using Sonovue as the contrast agent

Sponsors & Collaborators

• Shenzhen Children's Hospital

  collaborator OTHER_GOV

• Children's Hospital of Chongqing Medical University

  collaborator OTHER

• Tianjin Children's Hospital

  collaborator OTHER

• Kunming Children's Hospital

  collaborator OTHER

• Second Affiliated Hospital, School of Medicine, Zhejiang University

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Yuying Children's Hospital of Wenzhou Medical University

  collaborator OTHER

• Xian Children's Hospital

  collaborator OTHER_GOV

• The Children's Hospital of Zhejiang University School of Medicine

  lead OTHER

Eligibility

Min Age

29 Days

Max Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-09-10

Primary Completion

2026-09-30

Completion

2026-09-30

FDA Drug

Yes

Countries

• China

Study Locations