Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors
NCT07112989 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 125
Last updated 2025-08-08
Summary
The goal of this observational study is to learn how tumor tissue and blood samples from patients with sarcomas or metastases can be used to create laboratory models that help researchers study cancer behavior and test new treatments. Participants diagnosed with sarcoma or with bone or lung metastases from solid tumors will donate leftover tumor tissue and blood collected during their regular medical care. These samples will be used in the lab to build 3D models of the tumor, test drugs, and identify genetic and molecular markers. No treatments or procedures will be given as part of the study.
Conditions
- Bone and Soft Tissue Tumors
- Bone Metastases From Solid Tumors
- Lung Metastases
Sponsors & Collaborators
-
Istituto Ortopedico Rizzoli
lead OTHER
Eligibility
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-09-23
- Primary Completion
- 2031-09-23
- Completion
- 2031-09-23
Countries
- Italy
Study Locations
More Related Trials
-
Feasibility of Radioisotope-guided Excision of Mediastinal Lymph Nodes in Patients With Non-small Cells Lung Carcinoma
NCT05072561 ·Status: UNKNOWN ·Phase: NA
-
Molecular Phenotyping of Primitive Lung Cancer and Metastatic Site
NCT07325864 ·Status: RECRUITING
-
A Multi-center Prospective Observational Biomarker Study on EGFRm+ Non-small Cell Lung Cancer Patients With Leptomeningeal Metastasis
NCT02803619 ·Status: UNKNOWN
-
Feasibility Study of Tissue and Blood Collection in Oncogene-addicted and Neoadjuvantly Treated Non Small Cell Lung Cancer
NCT07008742 ·Status: RECRUITING
-
A Look Back at How Well Interventional Treatments Work for Bronchopleural Fistulas in Patients With Lung Metastases From Osteosarcoma
NCT06927596 ·Status: NOT_YET_RECRUITING
-
A Study of Local Ablative Therapy (LAT) in People With Non-Small Cell Lung Cancer (NSCLC)
NCT05429320 ·Status: COMPLETED ·Phase: PHASE2
-
Radical Resection With Contralateral Lymph Node Dissection for Clinical N3 NSCLC
NCT07003490 ·Status: RECRUITING ·Phase: NA
-
A Study to Explore Prognoses of NSCLC Patients Complicated With Oligometastases
NCT03427541 ·Status: UNKNOWN
-
An Observational Study to Explore Clinical Characteristics of the Patients With T1 Non-small Cell Lung Cancer
NCT03413956 ·Status: COMPLETED
-
Clinical Evaluation for Sarcoma Originated From Bone
NCT03358992 ·Status: UNKNOWN
-
Study on Clinical Features, Treatment Mode and Survival of Bone and Soft Tissue Tumors
NCT05468970 ·Status: RECRUITING
-
Spinal Metastasis as the First Presentation of Lung Malignancy: Clinical Characteristics and Postoperative Survival
NCT07100444 ·Status: COMPLETED
-
Influence of the Use of the Diabetic Drug Metformin on the Overall Survival and Treatment-related Toxicity in Advanced Stage Non-small Cell Lung Cancer Patients.
NCT02109549 ·Status: COMPLETED
-
Metformin in Non Small Cell Lung Cancer (NSCLC)
NCT02285855 ·Status: TERMINATED ·Phase: PHASE2
-
Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens
NCT06252129 ·Status: RECRUITING ·Phase: NA
-
Robotic Assisted Major Lung Resection in Elderly Patients
NCT06496386 ·Status: RECRUITING
-
Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects
NCT06800586 ·Status: RECRUITING
-
Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma
NCT04735289 ·Status: UNKNOWN
-
A Prospective, Multi-Center Evaluation of a Powered Vascular Stapler in Video-Assisted Thoracoscopic Lobectomies
NCT03056300 ·Status: COMPLETED ·Phase: NA
-
Clinical and Molecular Findings in Patients With Cervical/Supraclavicular Metastasis From Non-small-cell Lung Cancer (NSCLC)
NCT05706883 ·Status: COMPLETED
-
Predictive Models of Treatment Responses and Survival Outcomes in Patients With Osteosarcoma
NCT05194605 ·Status: UNKNOWN
-
A Prospective, Observational Trial on the Diagnostic and Prognostic of LM
NCT02607605 ·Status: UNKNOWN
-
Study of the Expression of Met Receptor Fragments in Non Small Cell Lung Cancers
NCT01647867 ·Status: COMPLETED ·Phase: NA
-
Phase II Study Evaluating Strategies of Lung Surveillance of Patients Operated of High Grade Soft Tissue Sarcoma
NCT01612481 ·Status: TERMINATED ·Phase: PHASE2
-
Verification of Novel Survival Prediction Algorithm for Patients With NSCLC Spinal Metastasis
NCT03363685 ·Status: UNKNOWN