A Phase II Study of Siltuximab for CRS/ICANs After CAR-T in Multiple Myeloma
NCT07106671 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2025-08-06
Summary
This is a prospective Phase II study evaluating Siltuximab for CRS and ICANS after CAR-T infusion in multiple myeloma patients.
Conditions
- CRS - Cytokine Release Syndrome
- Myeloma
Interventions
- DRUG
-
Siltuximab
Siltuximab 11mg/kg
Sponsors & Collaborators
-
Institute of Hematology & Blood Diseases Hospital, China
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-10
- Primary Completion
- 2026-08-01
- Completion
- 2027-08-01
Countries
- China
Study Locations
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