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Dexmedetomidine During Carotid Endarterectomy: a Registry on Safety and Satisfaction of Patients and Operators (DexTEA)

NCT07105527 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2025-08-12

No results posted yet for this study

Summary

From an anesthesiological perspective, carotid endarterectomy (CEA) is an operation that is increasingly being performed with locoregional techniques and sedation. The aim of this observational study was to compare dexmedetomidine with midazolam and fentanyl during CEA in terms of perioperative adverse events, patient, anesthetist, and surgeon satisfaction, as well as the possible reduction in clamping time and the number of times additional local anaesthesia is needed.

Sixty patients listed for CEA were enrolled and two types of sedation were used, both protocols widely used in our hospital, resulting in the formation of two groups of patients. Both the intermediate and superficial cervical plexus blocks were administered, and the patients in Group 1 were sedated with midazolam and fentanyl, and Group 2 was sedated with dexmedetomidine. The investigators examined comorbidities, surgical time and clamping, and possible intraoperative use of local anaesthetics and intraprocedural complications, and follow-up at 180 days to observe any residual deficits. The data were analysed with Statistical Package for Social Science (SPSS) Statistics 25 (IBM).

Conditions

  • Hypertension Arterial
  • Desaturation
  • Bradycardia
  • Surgery (Major Vascular)
  • Hypotension During Surgery
  • Dexmedetomidine Induced Sedation
  • Fentanyl Analgesia
  • Satisfaction, Patient
  • Satisfaction, Personal
  • Nausea/Vomiting

Sponsors & Collaborators

  • Saint Camillus International University of Health Sciences

    lead OTHER

Principal Investigators

  • Diego Fiume, MD PhD · UniCamillus - Saint Camillus International University of Health and Medical Sciences

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-08
Primary Completion
2023-02-02
Completion
2023-08-02

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07105527 on ClinicalTrials.gov