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MHT and Liver Function in Postmenopausal Women

NCT07103603 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2026-01-27

No results posted yet for this study

Summary

This prospective study aims to evaluate the effects of menopausal hormone therapy (MHT) on liver function, lipid profiles, and hepatic steatosis in postmenopausal women. A total of 44 participants will be divided into two groups: 22 received MHT and 22 were monitored without treatment. Biochemical parameters, FIB-4 scores, and attenuation imaging (ATI) measurements are assessed at baseline and after six months. The study investigates whether MHT is associated with favorable changes in liver enzymes, hepatic fat accumulation, and noninvasive fibrosis markers.

Conditions

  • Menopause
  • Non Alcholic Fatty Liver Disease
  • Hepatic Steatosis

Interventions

DRUG

Menopausal hormone therapy

Menopausal hormone therapy including oral or transdermal estrogen, with or without progestin, administered based on clinical indications.

Sponsors & Collaborators

  • Ipek B. Ozcivit Erkan, MD

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-30
Primary Completion
2025-09-30
Completion
2025-12-30

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07103603 on ClinicalTrials.gov