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COMPARISON OF ZINC AND PROBIOTICS ON NEONATES WITH INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY

NCT07102836 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 110

Last updated 2025-08-05

No results posted yet for this study

Summary

Study will evaluate effects of oral zinc and probiotics supplementation in neonates who have indirect hyperbilirubinemia and are receiving phototherapy. Aim is to compare efficacy of these two drugs in clearing bilirubin and reducing duration of phototherapy. Neonates will be randomly assigned to receive either drug alongside phototherapy.

Conditions

  • Indirect Hyperbilirubinemia
  • Neonatal

Interventions

DRUG

Zinc sulfate

Oral zinc sulfate syrup in a dose providing 5mg elemental zinc daily as adjuvant to phototherapy.

DRUG

Probiotic lactobacillus rhamnosus GG

Oral Probiotic Lactobacillus rhamnosus GG drops daily as adjuvant to phototherapy.

Sponsors & Collaborators

  • Quaid-e-Azam Medical College

    lead OTHER

Principal Investigators

  • Malik M. Umair Fazal, MBBS, FCPS Paediatrics · Quaid-e-Azam Medical College

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
0 Days
Max Age
28 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-07
Primary Completion
2026-02-07
Completion
2026-05-07

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07102836 on ClinicalTrials.gov