A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )
NCT07101328 · Status: NOT_YET_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 215
Last updated 2026-05-13
Summary
The purpose of this study is to find the best dose of the drug and measure the safety and efficacy of LY4152199 in participants with previously treated B-cell malignancies. Participants will have the option to continue taking LY4152199 until the study ends.
Conditions
- Lymphoma, Non-Hodgkin
- B-cell Lymphoma
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Follicular
- Lymphoma, B-cell Marginal Zone
- Waldenstrom Macroglobulinemia
- Lymphoma, Mantle Cell
Interventions
- DRUG
-
LY4152199 - IV
Administered by IV infusion
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST) · Eli Lilly and Company
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-06-30
- Primary Completion
- 2027-04-30
- Completion
- 2029-09-30
- FDA Drug
- Yes
Countries
- United States
- Australia
- Canada
- Denmark
- France
- Germany
- Italy
- Japan
- Poland
- South Korea
- Spain
- United Kingdom
Study Locations
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