MedTrace Logo

A Study to Predict Recompensation in Patients With Decompensated Cirrhosis Using Spleen Stiffness and Simple Blood Tests

NCT07087041 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 735

Last updated 2025-07-25

No results posted yet for this study

Summary

The goal of this observational study is to learn if spleen stiffness and other non-invasive markers can help predict recompensation in people with decompensated cirrhosis who are receiving effective treatment for the cause of their liver disease. The main questions it aims to answer are:

* Can spleen stiffness and blood test results predict who will get better and stay better after cirrhosis becomes worse?
* What are the features of people who recover after decompensation?

Participants will:

* Be people with decompensated cirrhosis who are already getting effective treatment (such as antiviral therapy or alcohol abstinence)
* Be followed over time to check if they remain stable or have more liver problems
* Have non-invasive tests done, including spleen stiffness measurement and blood tests

Researchers will track how many participants recover and stay recovered over time, and use that information to build a tool to help predict outcomes in others with cirrhosis.

Conditions

  • Decompensated Cirrhosis
  • Hepatitis B Virus (HBV) Infection
  • Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
  • Alcohol-Related Liver Disease
  • Portal Hypertension
  • Recompensation

Sponsors & Collaborators

  • Beijing Friendship Hospital

    lead OTHER

Principal Investigators

  • Hong You, Prof. · Beijing Friendship Hospital

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-15
Primary Completion
2028-10-30
Completion
2028-12-30

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07087041 on ClinicalTrials.gov