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Efficacy of Nitazoxanide Based Therapy vs Standard Triple Therapy in H-pylori in Children

NCT07086937 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2025-07-25

No results posted yet for this study

Summary

This study aimed at comparing the efficacy of nitazoxanide-based triple therapy versus standard triple therapy for eradication of Helicobacter pylori infection in children at a tertiary care hospital.

Conditions

  • Helicobacter Pylori Infection

Interventions

DRUG

Nitazoxanide

Children were given nitazoxanide, PPI, and clarithromycin for 14 days.

DRUG

Metronidazole

Children received MTZ, PPI, and clarithromycin for 14 days.

DRUG

PPI

Children were given omeprazole for 14 days.

DRUG

Clarithromycin

Children were given clarithromycin for 14 days.

Sponsors & Collaborators

  • Muhammad Aamir Latif

    lead OTHER

Principal Investigators

  • Shumaila Waseem · Ziauddin University Karachi

  • Heena Raees, FCPS · Ziauddin University Karachi

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
2 Years
Max Age
12 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-01
Primary Completion
2025-06-30
Completion
2025-06-30

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07086937 on ClinicalTrials.gov