A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
NCT07082738 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 1160
Last updated 2026-03-17
Summary
This Phase IIb dose-ranging study will evaluate the efficacy and safety of 3 different doses of AZD6793 compared with placebo tablets in participants with moderate to very severe chronic obstructive pulmonary disease.
Conditions
- Chronic Obstructive Pulmonary Disease (COPD)
Interventions
- DRUG
-
AZD6793
Oral dosage
- OTHER
-
Placebo
Oral dosage
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Dave Singh, MD · Medicines Evaluation Unit, Manchester University NHS Foundations Trust, Manchester, United Kingdom
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-06-27
- Primary Completion
- 2027-11-05
- Completion
- 2027-11-05
- FDA Drug
- Yes
Countries
- United States
- Argentina
- Australia
- Bulgaria
- Canada
- Chile
- China
- Denmark
- Germany
- Greece
- Hungary
- India
- Italy
- Japan
- Mexico
- Peru
- Poland
- South Korea
- Spain
- Taiwan
- Turkey (Türkiye)
- Ukraine
- United Kingdom
- Vietnam
Study Locations
More Related Trials
-
Study to Assess the Efficacy and Safety of AZD1981 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
NCT00690482 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871
NCT02971293 ·Status: COMPLETED ·Phase: PHASE2
-
A Two Week Study to Assess the Tolerability of AZD9668 in Chronic Obstructive Pulmonary Disease (COPD) Patients
NCT00703391 ·Status: COMPLETED ·Phase: PHASE2
-
The Study Will Evaluate the Effect of AZD8683 in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT01205269 ·Status: COMPLETED ·Phase: PHASE2
-
Tolerability/Safety and Efficacy of Inhaled AZD4818 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
NCT00629239 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects
NCT02814656 ·Status: COMPLETED ·Phase: PHASE1
-
Safety/Tolerability Study With AZD1236 in Chronic Obstructive Pulmonary Disease (COPD) Patients
NCT00758459 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase IIa Study to Investigate the Efficacy and Safety of AZD7624 in Chronic Obstructive Pulmonary Disease (COPD) Patients While on Maintenance Therapy
NCT02238483 ·Status: COMPLETED ·Phase: PHASE2
-
Effect on Structural Changes in Airways, Measured by MSCT, of Twice Daily 60mg AZD9668 for 12 Weeks in Chronic Obstructive Pulmonary Disease (COPD) Patients
NCT01054170 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Twice Daily 60mg AZD9668 in COPD for 12 Weeks in Patients on Background Budesonide/Formoterol
NCT01023516 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Investigate Safety, Tolerability and Effect of Multiple Dosing With AZD 4721 and/or With AZD 5069
NCT01962935 ·Status: COMPLETED ·Phase: PHASE1
-
Investigation of the Effect of Oral Treatment With 100 mg AZD2423 in Subjects With Mild Chronic Obstructive Pulmonary Disease (COPD)
NCT01153321 ·Status: COMPLETED ·Phase: PHASE2
-
14729-D9831C00002- 1 Month Biopsy Study
NCT00766415 ·Status: COMPLETED ·Phase: PHASE2
-
A Trial Assessing LAS34273 in Moderate to Severe Stable Chronic Obstructive Pulmonary Disease (COPD)
NCT00363896 ·Status: COMPLETED ·Phase: PHASE3
-
Multi-centre Study to Assess the Efficacy and Safety of AZD5423 in COPD Patients on a Background Therapy of Formoterol
NCT01555099 ·Status: COMPLETED ·Phase: PHASE2
-
A Single-dose Study to Investigate the Effects of 3 Different Doses of Inhaled AZD2115 in COPD Patients
NCT01498081 ·Status: COMPLETED ·Phase: PHASE2
-
Dose-Ranging Study Of GSK233705B In Subjects With Chronic Obstructive Pulmonary Disease (COPD)
NCT00676052 ·Status: COMPLETED ·Phase: PHASE2
-
AZD2115 Single Ascending Dose Study
NCT01283984 ·Status: COMPLETED ·Phase: PHASE1
-
A 4 Week Study to Investigate the Safety and Tolerability of AZD5069 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
NCT01233232 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis
NCT01255592 ·Status: COMPLETED ·Phase: PHASE2
-
To Assess the Safety, Tolerability, and Pharmacokinetics of AZD7624 in Healthy Volunteers and COPD Patients
NCT01817855 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD
NCT02343458 ·Status: COMPLETED ·Phase: PHASE3
-
A First Time in Man Study to Asses the Safety and Tolerability of AZD7624 in Healthy Subjects
NCT01754844 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess Safety, Tolerability and Pharmacokinetics of of AZD6553 in Healthy Volunteers and Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT01068184 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7594 Inhaled Formulation in Healthy Japanese Men
NCT02645253 ·Status: COMPLETED ·Phase: PHASE1