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Micellar Water and the Skin Barrier: Comparing Rinsing vs. Non-Rinsing Application

NCT07079371 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-07-23

No results posted yet for this study

Summary

The goal of this clinical trial is to assess how micellar water affects the skin barrier in healthy adult volunteers. The main questions it aims to answer are:

* Does leaving micellar water on the skin affect skin barrier function differently than rinsing it off?
* Are there measurable differences in transepidermal water loss (TEWL), skin hydration, and erythema between the two application methods?

Researchers will compare the effects of micellar water left on the skin versus rinsed off after application.

Participants will:

* Be randomly assigned to one of two groups
* Apply micellar water to their forehead once daily for 21 days
* Either leave the micellar water on or rinse it off, depending on their group
* Undergo non-invasive measurements of TEWL, skin hydration, and erythema before and after the intervention

Conditions

  • Effects of Micellar Water Application on Skin Barrier Integrity, Hydration, and Erythema in Healthy Skin

Interventions

PROCEDURE

Micellar Water Application (No Rinse)

Participants apply micellar water to the forehead once daily and leave it on the skin without rinsing for 21 days.

PROCEDURE

Micellar Water Application (With Rinse)

Participants apply micellar water to the forehead once daily and rinse it off after application for 21 days.

Sponsors & Collaborators

  • University of Split, School of Medicine

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-06-18
Primary Completion
2026-01-01
Completion
2026-01-01

Countries

  • Croatia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07079371 on ClinicalTrials.gov