Distance-Based Exercise to Preserve Function and Prevent Disability

Summary

This clinical trial studies whether an exercise program can be successfully delivered to patients receiving treatment for cancer through virtual sessions and allow patients to exercise in their own home. Treatments for cancer can cause side effects such as fatigue and loss of strength. These side effects can make it difficult to work, take care of family, and do other things the patient wants to do. Preliminary research shows that exercise can help prevent some of these side effects, but it can be more difficult to start an exercise program when a patient is receiving cancer treatment. The exercise program in this study is delivered through telehealth (TH) video calls. The TH sessions are delivered by trained staff that supervise resistance exercises. The trained staff also provide guidance to the patient on completing unsupervised aerobic sessions on their own. This may be a successful way to deliver an exercise program and make it easier for cancer patients to exercise in their own home during treatment.

Conditions

• Localized Malignant Solid Neoplasm
• Anal Cancer
• Bladder (Urothelial, Transitional Cell) Cancer
• Breast Cancer
• Cervical Cancer
• Colon Cancer
• Endometrial Cancer
• Esophageal Cancer
• Gall Bladder Cancer
• Gastric Cancer
• Kidney Cancer
• Liver Cancer
• Lung Cancer
• Head and Neck Cancer
• Ovarian Cancer
• Pancreatic Cancer
• Prostate Cancer
• Rectal Cancer
• Sarcoma

Interventions

OTHER

Exercise intervention

Complete supervised TH aerobic and progressive resistance exercise sessions

OTHER

Telemedicine

Complete supervised TH aerobic and progressive resistance exercise sessions

OTHER

Aerobic Exercise Intervention

Complete unsupervised aerobic exercise

OTHER

Exercise Intervention

Receive stationary bike, workbook, gloves, and resistance bands

PROCEDURE

Accelerometry

Wear accelerometer

OTHER

Questionnaire Administration

Ancillary studies

OTHER

Interview

Ancillary studies

OTHER

Electronic Health Record Review

Ancillary studies

Sponsors & Collaborators

• National Cancer Institute (NCI)

  collaborator NIH

• Alliance for Clinical Trials in Oncology

  lead OTHER

Principal Investigators

• Jennifer Ligibel, MD · Alliance for Clinical Trials in Oncology

• Kathryn Schmitz, MD · Alliance for Clinical Trials in Oncology

Study Design

Allocation

NA

Purpose

SUPPORTIVE_CARE

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-02-11

Primary Completion

2027-07-01

Completion

2027-08-31

Countries

• United States

Study Locations