MedTrace Logo

Technologies and Systems for Assessing Human Energy Metabolism and Nutritional Rehabilitation

NCT07056504 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2025-09-02

No results posted yet for this study

Summary

The objective of this observational study is to integrate the doubly labeled water (DLW) database from healthy individuals with multimodal data-including, but not limited to, weight, height, age, sex, race, elevation-from cohorts undergoing rehabilitation following movement impairments or neurological injuries. Machine learning algorithms will be used to develop injury-specific predictive models of energy requirements.

The primary research question is:

How does energy metabolism change during the rehabilitation process in individuals recovering from traumatic brain injury, stroke, or major surgical procedures? To answer this, participants will undergo a comprehensive set of assessments, including measurements of height and weight, body composition, resting metabolic rate, physical activity levels, total energy expenditure, psychological health, food intake and hunger ratings, sleep quality, cognitive performance, non-invasive brain function monitoring, and gait analysis. Fecal and blood samples will also be collected for untargeted metabolomics analysis.

Conditions

  • Energy Metabolism
  • Nutrition, Healthy

Sponsors & Collaborators

  • Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

    lead OTHER

Principal Investigators

  • Xueying Zhang, PhD · Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

  • John R Speakman, PhD · Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-09
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07056504 on ClinicalTrials.gov