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Antimicrobial Impact of Various RC Final Irrigation Activation Techniques

NCT07056127 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2025-07-09

No results posted yet for this study

Summary

This randomized clinical study aims to evaluate microbial reduction in root canals after using different final irrigation activation techniques including passive ultrasonic irrigation, XP-endo Finisher file and Laser ablation with Indocyanine green dye in comparison to manual dynamic activation.

Conditions

  • Root Canal Final Irrigation Activation Techniques

Interventions

OTHER

manual dynamic agitaion

5 mL of 2.5% NaOCl solution will be activated with a well-fitting gutta-percha cone that will be placed to full working length and then will be moved in push-pull strokes of 2 mm amplitude at a frequency of 100 strokes in about 1 min

OTHER

ultrasonic activation

5 mL of 5.25% NaOCl solution will be activated with PUI using a #20 endosonic file that will be driven by an ultrasonic device on medium power setting for 1 minute and inserted 1 mm short of the working length

OTHER

xp-endo finisher

5 mL of 5.25% NaOCl solution will be activated with XP-Endo Finisher which will be used in the canal for 1 minute at 800 rpm and 1 Ncm up to the working length and in slow up-and-down movements at 7-8mm length according to the manufacturer's recommendations

OTHER

laser

First, root canals will be filled with 0.5 mL of 0.05% ICG dye and left in place for 1 minute as preirradiation time. A #20 laser fiber will be inserted into the root canals to the working length. Then infrared diode laser with a wave length of 810 nm will be used to activate the dye for 30 seconds. For activation, circular movements will be performed along with the fiber removal movement . After the first activation, dye will be reintroduced, the laser fiber will be inserted again, and a new activation cycle of 30 seconds will be performed similarly to the previous one

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
15 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-01
Primary Completion
2026-08-01
Completion
2026-09-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07056127 on ClinicalTrials.gov