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H-Reflex Suppression by Bone Myoregulation Reflex During Mechanical Loading in Standing Humans

NCT07043595 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2025-09-04

No results posted yet for this study

Summary

This study aims to investigate how standing posture and mechanical loading affect reflex responses in the lower limb. Specifically, it focuses on the H-reflex-a type of spinal cord reflex-and how it changes during quiet standing and whole-body vibration. Ten healthy adult volunteers will participate. Researchers will record electrical responses from the calf muscle (soleus) while participants stand still or are exposed to gentle vibration. The goal is to better understand how the nervous system and skeletal system interact in regulating balance and movement.

Conditions

  • H-reflex
  • Spinal Reflexes
  • Posture
  • Weight-Bearing
  • Neuromuscular Physiology

Interventions

PROCEDURE

Whole-Body Vibration (WBV)

Participants will stand quietly in an upright position while whole-body vibration (WBV) is applied through a vibration platform. The vibration stimulus is delivered while the participant's left foot remains on the vibration surface and the right foot is elevated or isolated. H-reflex recordings are taken from the soleus muscle during the procedure to assess spinal reflex modulation due to mechanical loading.

Sponsors & Collaborators

  • Istanbul Physical Medicine Rehabilitation Training and Research Hospital

    lead OTHER_GOV

Principal Investigators

  • Selim Sezikli, MD · Istanbul Physical Medicine and Rehabilitation Training and Research Hospital

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-06-24
Primary Completion
2025-07-07
Completion
2025-07-10

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07043595 on ClinicalTrials.gov