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Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective Study

NCT07037706 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2025-06-25

No results posted yet for this study

Summary

This study looks at whether using macrolide antibiotics is helpful and safe in treating acute chest syndrome, a serious complication in people with sickle cell disease. It reviews past cases from three hospitals where patients were treated in intensive care. The goal is to understand if macrolides make a difference, what germs are involved, how useful lab tests are, and how well patients tolerate these antibiotics.

Conditions

  • Sickle Cell Disease
  • Acute Chest Syndrome
  • Glucose-6-Phosphate Dehydrogenase Deficiency
  • Anti-Bacterial Agents
  • Macrolides

Sponsors & Collaborators

  • Centre Hospitalier de Saint-Denis

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-06-01
Primary Completion
2024-06-01
Completion
2024-06-01

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07037706 on ClinicalTrials.gov