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Clinical Trial of PCSK9 Inhibitor and Statin Treatment for Carotid Artery Stenosis

NCT07036991 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 406

Last updated 2025-06-25

No results posted yet for this study

Summary

A prospective, multicenter, randomized controlled, open-label, blinded outcome evaluation (PROBE) trial.

Conditions

  • Carotid Artery Stenosis

Interventions

DRUG

Evolocumab (biweekly injections) + Rosuvastatin/Atorvastatin ± Ezetimibe

PCSK9 inhibitor (biweekly injections) + rosuvastatin/atorvastatin ± ezetimibe

DRUG

Rosuvastatin/Atorvastatin ± Ezetimibe

Rosuvastatin/atorvastatin ± ezetimibe

Sponsors & Collaborators

  • The First Affiliated Hospital of Soochow University

    collaborator OTHER

  • Changhai Hospital

    lead OTHER

Principal Investigators

  • Jianmin Liu · Changhai Hospital

  • Pinjing Hui, MD, PhD · The First Affiliated Hospital of Soochow University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-30
Primary Completion
2026-06-01
Completion
2027-03-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07036991 on ClinicalTrials.gov