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Detecting Fatigue From Voice in Generalised Myasthenia Gravis

NCT07033559 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 240

Last updated 2026-01-28

No results posted yet for this study

Summary

The goal of this observational study is to learn if computer analysis of voice recordings can detect a type of exhaustion called "central fatigue" in adults with generalised myasthenia gravis.

The main questions it aims to answer are:

1. Can advanced voice analysis accurately tell when participants are experiencing deep exhaustion based on how they speak?
2. How easy and acceptable is voice-based fatigue monitoring for people with myasthenia gravis?

Participants will:

1. Record themselves reading short passages and answering questions out loud twice daily (morning and evening), twice a week, for 4 weeks.
2. Answer brief questionnaires about their energy levels, mood, and myasthenia gravis symptoms during each session.
3. Use their own devices (computer, tablet, or smartphone) to complete all study activities online from home.

Conditions

  • Myasthenia Gravis Generalised

Sponsors & Collaborators

  • UCB Pharma

    collaborator INDUSTRY

  • Thymia Limited

    lead INDUSTRY

Principal Investigators

  • Alexandra L Georgescu, PhD · Thymia Limited

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-28
Primary Completion
2026-06-30
Completion
2026-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07033559 on ClinicalTrials.gov