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Genicular Embolization Using Doxycycline Sclerotherapy

NCT07024654 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL

Last updated 2026-02-27

No results posted yet for this study

Summary

The goal of this prospective case series is to develop an alternative pain management procedure for patients who are not surgical candidates. The main question it aims to answer is: Is genicular sclerotherapy using doxycycline a safe and effective pain management option for patients with chronic knee pain who are not surgical candidates?

OUTCOME MEASURES:

Primary: Visual Analog Scale (VAS) score at 3 months

Secondary:

* VAS at 12 months
* Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score at 12 months

Conditions

Interventions

DRUG

Doxycycline Injection

Injection of doxycycline as a sclerosing agent into the genicular artery region under ultrasound guidance for the purpose of evaluating its effectiveness in reducing knee pain.

Sponsors & Collaborators

  • Campbell Clinic

    lead OTHER

Principal Investigators

  • Joshua Brandon, MD · Campbell Clinic

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-30
Primary Completion
2027-06-30
Completion
2029-06-30
FDA Drug
Yes

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07024654 on ClinicalTrials.gov