MedTrace Logo

Post-Implantation Syndrome and Laboratory Markers Following EVAR and TEVAR

NCT07014839 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2025-06-11

No results posted yet for this study

Summary

The aim of this observational study is to investigate the relationship between postimplantation syndrome (PIS) and laboratory inflammatory parameters following endovascular aortic repair (EVAR/TEVAR). PIS is a systemic inflammatory response that may occur after EVAR or TEVAR and lacks a standardized clinical definition. This study seeks to determine whether specific laboratory biomarkers-particularly white blood cell count, C-reactive protein (CRP), interleukin levels, and neutrophil-to-lymphocyte ratio (NLR)-can serve as reliable indicators for the diagnosis and assessment of PIS.

Conditions

  • Postimplantation Syndrome
  • Endovascular Abdominal Aortic Aneurysm Repair (EVAR)
  • Thoracic Endovascular Aortic Repair

Interventions

PROCEDURE

Endovascular Aortic Intervention

This intervention involves EVAR or TEVAR for the treatment of abdominal or thoracic aortic aneurysms, respectively. The procedures were performed using commercially available stent-grafts via a transfemoral approach under standard perioperative protocols. The study specifically focuses on the systemic inflammatory response following these interventions, with close monitoring of laboratory parameters including IL-6, neutrophil-to-lymphocyte ratio (NLR), CRP, leukocyte count, and procalcitonin during the early postoperative period. No adjunctive anti-inflammatory or immunomodulatory therapies were administered.

Sponsors & Collaborators

  • Ataturk University

    lead OTHER

Principal Investigators

  • umit arslan · Ataturk University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-01
Primary Completion
2024-12-31
Completion
2025-04-15

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07014839 on ClinicalTrials.gov