A Study to Assess the Effects of BPN14770 on Rosuvastatin
NCT07011992 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2025-08-14
Summary
The primary objective of this study is to investigate the effects of BPN14770 on the pharmacokinetics of the breast cancer resistance protein and organic anion transporting polypeptide 1B1 substrate rosuvastatin in healthy adults.
Conditions
- Healthy Participants
Interventions
- DRUG
-
Rosuvastatin
Oral tablet
- DRUG
-
BPN14770
Oral capsule
Sponsors & Collaborators
-
Shionogi
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-07-18
- Primary Completion
- 2025-07-31
- Completion
- 2025-08-07
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Clinical Trial to Investigate the Clinical Drug-Drug Interaction of Divarasib With Probe Substrates of P-Glycoprotein and Breast Cancer Resistance Protein in Healthy Participants
NCT06677957 ·Status: COMPLETED ·Phase: PHASE1
-
Drug-drug Interaction Study of GSK1278863 With Pioglitazone, Rosuvastatin and Trimethoprim in Healthy Adult Volunteers
NCT02371603 ·Status: COMPLETED ·Phase: PHASE1
-
A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions
NCT03136237 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Pioglitazone Hydrochloride When Given Together to Healthy Subjects
NCT01088919 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic Interactions of Bisoprolol and Rosuvastatin
NCT01925300 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Drug Interaction Study Between Bosutinib And Aprepitant In Healthy Volunteers
NCT02058277 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Lazertinib (JNJ-73841937) in Healthy Participants
NCT05076877 ·Status: COMPLETED ·Phase: PHASE1
-
A Drug Drug Interaction Study to Evaluate the Effect of VCT220 on the Pharmacokinetics of Repaglinide, Rosuvastatin, and Digoxin in Healthy, Overweight, and Obese Subjects
NCT07065058 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Effect of Oral Belumosudil on Inhibition of Various Proteins in the Fed State in Healthy Male Subjects
NCT05806567 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Pexidartinib on the Way the Body Processes CYP3A4 and CYP2C9 Substrates (Pharmacokinetics)
NCT03291288 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Effects of Itraconazole, Food, and pH on the Drug Levels of BMS-986368 in Healthy Participants
NCT06170723 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male Subjects
NCT05768360 ·Status: COMPLETED ·Phase: PHASE1
-
Drug-Drug Interaction Study With PF-05089771
NCT01934569 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate Drug-drug Interactions Between BR1017-1 and BR1017-2 in Healthy Volunteers
NCT05372380 ·Status: COMPLETED ·Phase: PHASE1
-
Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s
NCT03457597 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Participants
NCT05965570 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Pharmacokinetic Interaction and Safety After Multiple Oral Doses of Fimasartan/Amlodipine and Rosuvastatin in Healthy Male Subjects
NCT02397538 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Sitagliptin When Given Together to Healthy Subjects
NCT01104532 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Effect of Itraconazole, Phenytoin and Gemfibrozil on the Drug Levels of BMS-986166 in Healthy Participants
NCT04956627 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Itraconazole on the Pharmacokinetics of Apatinib
NCT02836171 ·Status: COMPLETED ·Phase: PHASE1
-
Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir
NCT05236530 ·Status: COMPLETED ·Phase: PHASE1
-
Drug-Drug Interaction Study of TRK-100STP
NCT00719758 ·Status: COMPLETED ·Phase: PHASE1
-
A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy Participants
NCT06111521 ·Status: COMPLETED ·Phase: PHASE1
-
PRC-4016 (Icosabutate) Phase I Drug-drug Interaction Study
NCT02367937 ·Status: COMPLETED ·Phase: PHASE1
-
Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin
NCT04231435 ·Status: COMPLETED ·Phase: PHASE1