MedTrace Logo

Comparative Analysis of Postoperative Manometry Outcomes in Nissen vs Toupet Fundoplication

NCT06986902 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2025-05-23

No results posted yet for this study

Summary

This randomized controlled trial investigates the effects of laparoscopic Nissen and Toupet fundoplication on postoperative esophageal manometry findings in patients with gastroesophageal reflux disease (GERD). The study, conducted at Ain Shams University Hospitals, involved 20 adult patients randomly assigned to undergo either procedure. Preoperative and postoperative high-resolution manometry (HRM) was used to assess lower esophageal sphincter (LES) pressure and esophageal motility.

Conditions

  • GERD - Gastro-Esophageal Reflux Disease

Interventions

PROCEDURE

Laparoscopic Nissen Fundoplication

a 360° total wrap of the gastric fundus around the esophagus.

PROCEDURE

Laparoscopic Toupet fundoplication

a 270° posterior partial wrap of the gastric fundus around the esophagus.

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Edward A Gadalla, MS · Assistant lecturer in General surgery Department , Ain shams University Hospitals

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-10
Primary Completion
2025-03-15
Completion
2025-03-15

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06986902 on ClinicalTrials.gov