Effectiveness of ERAS on Postoperative Recovery After Minimally Invasive Gastrectomy

Summary

This prospective, randomized, open-label, multicenter study is designed to evaluate the impact of an enhanced recovery after surgery (ERAS) protocol on the rate of meeting discharge criteria in patients undergoing minimally-invasive gastrectomy for gastric cancer. We hypothesize that implementation of our ERAS protocol will significantly increase the proportion of patients who meet standardized discharge criteria following minimally-invasive gastrectomy.

Conditions

• Enhanced Recovery After Surgery
• Gastrectomy for Gastric Cancer

Interventions

PROCEDURE

ERAS protocol

The ERAS protocol includes pre-admission patient education through audiovisual materials; reduction of perioperative fasting duration with preoperative carbohydrate loading and early postoperative oral intake; multimodal prophylaxis for postoperative nausea and vomiting; early removal of surgical drains and intravenous lines; early mobilization; and multimodal analgesia aimed at minimizing postoperative opioid use. The detailed protocol used in this study has been published previously \[https://doi.org/10.5230/jgc.2025.25.e27\].

Sponsors & Collaborators

• Seoul National University Bundang Hospital

  collaborator OTHER

• Seoul National University Boramae Hospital

  collaborator OTHER

• Severance Hospital

  collaborator OTHER

• Chungnam National University Hospital

  collaborator OTHER

• Keimyung University Dongsan Medical Center

  collaborator OTHER

• National Cancer Center, Korea

  collaborator OTHER_GOV

• The Catholic University of Korea

  collaborator OTHER

• Ajou University School of Medicine

  collaborator OTHER

• Pusan National University Hospital

  collaborator OTHER

• Seoul National University Hospital

  lead OTHER

Principal Investigators

• Do Joong Park, MD, PhD · Seoul National University Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

19 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-06-13

Primary Completion

2028-12-31

Completion

2029-03-31

Countries

• South Korea

Study Locations