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Neurolytic Block Techniques In Abdominal Visceral Cancer Pain

NCT06978673 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2025-06-03

No results posted yet for this study

Summary

The neurolytic blocks of sympathetic chains are commonly used for the treatment of cancer-related pain. This study aims to compare celiac plexus neurolysis and splanchnic nerve neurolysis for the treatment of abdominal visceral pain and its influence on the quality of life of patients with cancer.

Conditions

  • Cancer, Malignant Tumors
  • Abdominal Cancer
  • Cancer Pain
  • Visceral Pain
  • Cancer-related Pain
  • Pain Management
  • Celiac Ganglia
  • Sympathetic Ganglia

Interventions

PROCEDURE

Splanchnic nerve neurolysis - 5 ml of absolute alcohol (100%)

Splanchnic neurolysis will be performed with 5 ml of absolute alcohol on each side at the level of the eleventh thoracic vertebra.

PROCEDURE

Celiac Plexus Neurolysis - 5 ml of absolute alcohol (100%)

Celiac plexus neurolysis will be performed with 5 ml of absolute alcohol on each side at the level of the first lumbar vertebra.

Sponsors & Collaborators

  • Instituto do Cancer do Estado de São Paulo

    lead OTHER

Principal Investigators

  • Angela M Sousa, MD. PhD. · Instituto do Cancer do Estado de São Paulo

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-30
Primary Completion
2026-05-31
Completion
2026-12-31

Countries

  • Brazil

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06978673 on ClinicalTrials.gov