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Endocrine Disruptors, Toxic and Essential Chemical Elements and Polycystic Ovary Syndrome

NCT06968455 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2025-05-13

No results posted yet for this study

Summary

Studies have shown that endocrine disruptors (EDs) and toxic and essential chemical elements affect women's reproductive health and may play a role in the development of polycystic ovary syndrome (PCOS). There is little research examining the association of EDs and toxic and essential chemical elements with PCOS, and for some chemical compounds there is none. In our study, we will examine the relationship of EDs (bisphenols, parabens, triclosan) and toxic (cadmium-Cd, lead-Pb, mercury-Hg, arsenic-As) and essential chemical elements (selenium-Se, copper-Cu, zinc-Zn, manganum-Mn, molibdenum-Mo) in biological samples (blood, urine) of women with PCOS. Main hypothesis is that the levels of EDs, toxic chemical elements and molibdenum-Mo in the biological samples of PCOS women will be higher, and the levels of essential chemical elements will be lower than in the control group and related to the altered liver and kidney function and to the women's lifestyle and the environment they live in.

Conditions

  • Polycystic Ovary Syndrome

Interventions

OTHER

parabens

endocrine disruptors

Sponsors & Collaborators

  • University Medical Centre Ljubljana

    lead OTHER

Principal Investigators

  • Irma Virant-Klun, PhD · Clinical Research Centre, University Medical Centre Ljubljana

Eligibility

Min Age
20 Years
Max Age
39 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-03
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • Slovenia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06968455 on ClinicalTrials.gov