Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
NCT06966024 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2026-05-20
Summary
This is a multicenter clinical trial to evaluate the safety and preliminary activity of the selective general control nonderepressible 2 (GCN2) activator DCC-2812 as monotherapy in advanced/metastatic renal cell carcinoma (RCC), urothelial carcinoma, and castration-resistant prostate cancer.
Conditions
- Renal Cell Carcinoma
- Urothelial Carcinoma
- Castration-resistant Prostate Cancer
Interventions
- DRUG
-
DCC-2812
Administered orally
Sponsors & Collaborators
-
Deciphera Pharmaceuticals, LLC
lead INDUSTRY
Principal Investigators
-
Clinical Team · Deciphera Pharmaceuticals, LLC
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-27
- Primary Completion
- 2029-02-28
- Completion
- 2029-02-28
- FDA Drug
- Yes
Countries
- United States
Study Locations
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