Thyroidectomy for Graves' Disease or Amiodarone-induced Thyrotoxicosis

Summary

The goal of this observational study is to learn about the potential differences in morbidity of thyroidectomy (removal of the thyroid gland) depending on the preoperative hormonal status. The main question it aims to answer is:

Do patients undergoing thyroidectomy for thyreotoxicosis (thyroid hyperfunction) due to Graves' disease or Amiodarone induced thyreotoxicosis have comparable complication rates depending on their thyroid metabolic status prior or during the procedure.

The data from participants undergoing a thyroidectomy at one of the study sites will be prospectively registered in the EUROCRINE registry, including an add-on module for additional study specific routine data. The operation itself, the preoperative or postoperative treatments are not altered in any way.

Conditions

• Graves Disease
• Amiodarone-Induced Thyrotoxicosis
• Thyroidectomy

Sponsors & Collaborators

• Spital Männedorf

  collaborator UNKNOWN

• Spital Limmattal Schlieren

  collaborator OTHER

• Centre Hospitalier Universitaire Vaudois

  collaborator OTHER

• Ospedale Regionale di Mendrisio

  collaborator OTHER

• Kantonsspital St. Gallen, Switzerland

  collaborator UNKNOWN

• Cantonal Hosptal, Baselland

  collaborator OTHER

• St. Claraspital AG

  collaborator OTHER

• University Hospital, Geneva

  collaborator OTHER

• Insel Gruppe AG, University Hospital Bern

  collaborator OTHER

• ASZ Aalst

  collaborator OTHER

• University Hospital Virgen de las Nieves

  collaborator OTHER

• University of Nancy

  collaborator OTHER

• Hospital Costa del Sol

  collaborator OTHER

• Evgenidion Hospital Athens, Greece

  collaborator UNKNOWN

• Andrea Goldmann

  lead OTHER

Principal Investigators

• Andrea Goldmann, MD · Kantonsspital Winterthur KSW

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-07-01

Primary Completion

2027-06-30

Completion

2027-12-31

Countries

• Belgium
• France
• Greece
• Spain
• Switzerland

Study Locations