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Bone Metabolism in Premenopausal Exercising Women

NCT06961773 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2025-05-08

No results posted yet for this study

Summary

The main goal of this study is to examine how sex hormones and low energy availability affect the concentrations of bone remodelling markers at rest and after a running protocol. The research questions to be addressed are:

1: Does the ovarian hormone profile influence serum bone marker concentrations in women exercising resting and in response to to exercise?

2\. Are there differences in response to low energy availability in bone marker concentrations between eumenorrhoeic female athletes and oral contraceptive users?

3: Is the response of bone markers affected by different exercise stimuli: endurance or aerobic endurance?

4: Do bone markers return to baseline levels after 24 hours of high energy availability diet after 6 days of low energy availability?

Conditions

  • Contraception
  • Bone Metabolism
  • Low Energy Availability
  • Eumenorrhea

Interventions

OTHER

Low energy availability

Participants follow 6 days of a low-energy availability diet. The kilocalories of each diet are prescribed individually based on their fat-free mass.

OTHER

High energy availability

Participants follow 6 days of a high-energy availability diet. The kilocalories of each diet are prescribed individually based on their fat-free mass.

Sponsors & Collaborators

  • Universidad Politecnica de Madrid

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-12-05
Primary Completion
2025-12-20
Completion
2026-06-15

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06961773 on ClinicalTrials.gov