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Resilience Among Individuals With Opioid Use Disorder

NCT06954402 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 125

Last updated 2026-05-15

No results posted yet for this study

Summary

The goal of this clinical trial is to develop a human laboratory model of resilience in people with opioid use disorder (OUD). The investigators aim to learn if objective tasks that measure cognitive, emotional, and control aspects of resilience match up with self-reported resilience during stress and non-stress situations.

Conditions

Interventions

BEHAVIORAL

Acute Stress Intervention (MAST-based)

This intervention uses the Maastricht Acute Stress Test (MAST) to induce an acute stress response. Participants are exposed to standardized stress tasks while performing laboratory-based assessments of cognitive, emotional, and control aspects of resilience.

BEHAVIORAL

Non-Stress Intervention (NST-based)

In this control intervention, participants complete the same battery of laboratory tasks without exposure to the acute stressor.

Sponsors & Collaborators

Principal Investigators

  • Suky Martinez, PhD · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-29
Primary Completion
2029-04-30
Completion
2029-04-30

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06954402 on ClinicalTrials.gov