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Remotely Monitored, Mobile Health-supported, High Intensity Interval Training Before Hematopoietic Stem Cell Transplant

NCT06953648 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 126

Last updated 2025-05-01

No results posted yet for this study

Summary

The goal of this clinical trial is to learn how a remotely monitored high-intensity interval training (REMM-HIIT) affects the cardiorespiratory fitness and physical function for patients planning to undergo stem cell transplantation. The main questions it aims to answer are:

Is there a change in the participant's cardiorespiratory fitness level? Is there a change in the participant's physical function?

Researchers will compare the REMM-HIIT program to a control group of participants who do not take part in the training program to see if REMM-HIIT helps improve stem cell transplantation outcomes.

Participants will:

* Complete cardiopulmonary exercise testing (CPET) 4 times during the study
* Do basic tests to measure physical function 6 times during the study
* Answer questions about their life and how they are feeling 6 times during the study
* Wear a device to keep track of step counts and heart rate daily
* Keep a log of every time they exercise throughout the study
* Optionally, provide blood and stool samples 6 times during the study

Conditions

  • Hematopoietic Stem Cell Transplantation
  • Cardiorespiratory Fitness

Interventions

BEHAVIORAL

High Intensity Interval Training

The intervention will consist of three 30-minute training sessions/week, each starting with a five-minute warm-up, followed by 20 minutes of interval training, and ending with a five-minute cool-down. The interval training will consist of 10 alternating high- and low-intensity intervals, with a 1:1 work-to-rest ratio (one minute of high intensity followed by one minute of low-moderate intensity). As participants' fitness improves, the interval intensity will increase accordingly.

Sponsors & Collaborators

  • University of Kansas Medical Center

    lead OTHER

Principal Investigators

  • Anthony Sung, MD · The University of Kansas Cancer Center

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-31
Primary Completion
2028-10-31
Completion
2030-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06953648 on ClinicalTrials.gov