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Role of Frozen Section in Categorization of Thyroid Follicular Neoplasm

NCT06947629 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2025-04-27

No results posted yet for this study

Summary

The goal of this prospective study is to assess the effectiveness of frozen section in distinguishing between benign and malignant tumors in the category of follicular thyroid neoplasm to prevent over-surgery for benign follicular neoplasm (lobectomy Vs total thyroidectomy).

The main questions, it aims to answer are:

The follicular neoplasm is benign or malignent? how far is FNAC valid and accurate? Researchers will compare the results of frozen section and paraffin embedded sections to evaluate the validity and accuracy of FNAC.

Conditions

  • Role of Frozen Section in Categorization of Thyroid Follicular Neoplasm

Interventions

DIAGNOSTIC_TEST

Intraoperative Frozen Section

Intraoperative Frozen Section analysis which will include the following steps: \- The specimen will undergo both gross and microscopic examination: 1. Gross examination: Evaluation of nodular features including, multiplicity, size, outlines, color and consistency. 2. Microscopic examination: Assessment of capsular pattern, capsular invasion, thickness of capsule, vascular invasion and number of invaded vessels and the presence or absence of papillary structures.

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Howayda I Hassan, professor · Faculty of Medicine, Assiut Universiy, Assiut, Egypt

  • Mahmoud F Sherif, Assistant Professor · Faculty of Medicine, Assiut Universiy, Assiut, Egypt

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-02
Primary Completion
2026-07-01
Completion
2027-05-02

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06947629 on ClinicalTrials.gov