Validation of a miRNA Panel to Optimize Treatment Response in Patients With Metastatic Pancreatic Cancer (mirPANC 2)
NCT06945978 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2025-04-27
Summary
This study is being conducted to better understand how pancreatic cancer behaves during treatment and how we can improve methods for monitoring disease progression. The research aims to determine whether small molecules present in the blood, called miRNAs, can help doctors assess whether the treatment is working or needs adjustment. With this, we hope to make cancer monitoring less invasive and more precise, allowing patients to receive more personalized and effective treatments.
Conditions
- Pancreatic Cancer
- Metastasis
- Epigenetic
Sponsors & Collaborators
-
Benedito Mauro Rossi
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-01-21
- Primary Completion
- 2027-10-31
- Completion
- 2027-12-31
Countries
- Brazil
Study Locations
More Related Trials
-
Second Line Treatment With Nal-IRI and S1 in Pancreatic Cancer
NCT03986294 ·Status: UNKNOWN ·Phase: PHASE2
-
Personalized Tumor Neoantigen MRNA Therapy for Advanced Pancreatic Cancer.
NCT06888648 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
NCT04665947 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Study of Therapy Selected by Molecular/Metabolic Profiling in Patients With Previously Treated Metastatic Pancreatic Cancer
NCT01196247 ·Status: COMPLETED ·Phase: PHASE2
-
Identification of Biomarkers for Early Detection of Pancreatic Cancer
NCT00897494 ·Status: COMPLETED
-
Study of MM-398 With or Without 5-FU/LV, Versus 5-FU/LV in Patients With Metastatic Pancreatic Cancer
NCT01494506 ·Status: COMPLETED ·Phase: PHASE3
-
Minimally Invasive Detection of Lymphatic Micrometastases in Pancreatic Cancer
NCT00826982 ·Status: COMPLETED
-
Sorafenib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer
NCT00114244 ·Status: COMPLETED ·Phase: PHASE2
-
Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer
NCT04493060 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Gemcitabine and Erlotinib Plus Sorafenib (GES) in Metastatic Pancreatic Cancer
NCT00696696 ·Status: COMPLETED ·Phase: PHASE2
-
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
NCT06998940 ·Status: RECRUITING ·Phase: PHASE3
-
Gemcitabine, Bevacizumab and Erlotinib in Pancreatic Cancer
NCT00366457 ·Status: COMPLETED ·Phase: PHASE2
-
Niraparib as First Line Therapy With Metastatic Homologous Repair-deficient Pancreatic Cancer
NCT05442749 ·Status: TERMINATED ·Phase: PHASE2
-
NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer
NCT06941857 ·Status: RECRUITING ·Phase: PHASE2
-
Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer Patients
NCT05929885 ·Status: RECRUITING ·Phase: PHASE2
-
An Open-label, Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic Pancreatic Cancer
NCT03989310 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of Narmafotinib Given in Combination With Modified FOLFIRINOX in Patients With Metastatic Pancreatic Cancer
NCT07026279 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Gemcitabine and Monoclonal Antibody Therapy in Treating Patients With Metastatic Cancer of the Pancreas
NCT00003797 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase 2 Study of S-1 as 2nd Line Therapy in Metastatic Pancreatic Cancer
NCT00652054 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan Liposome in Combination With Capecitabine
NCT06578052 ·Status: RECRUITING ·Phase: NA
-
A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer
NCT02399137 ·Status: COMPLETED ·Phase: PHASE2
-
Combination of Anti-PD-1 Antibody and Chemotherapy in Metastatic Pancreatic Cancer
NCT03977272 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial Evaluating Low Dose G-FLIP Plus Mitomycin C for Stage IV Pancreatic Cancer
NCT06233877 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Molecularly Tailored Therapy to Standard of Care as Second-Line Therapy in Metastatic Pancreatic Cancer
NCT02967770 ·Status: WITHDRAWN ·Phase: PHASE2
-
Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma
NCT05262855 ·Status: COMPLETED ·Phase: PHASE2