A Study to Investigate the Safety, Tolerability and Pharmacodynamics of AZD4144 in Participants With Obesity
NCT06942923 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2025-10-07
Summary
The aim of this study is to evaluate the safety and tolerability, and pharmacodynamics (PD) of AZD4144 administered as repeated daily oral dosing.
Conditions
- Healthy Participants
Interventions
- DRUG
-
AZD4144
AZD4144 will be administered orally as per arms they have been assigned.
- DRUG
-
Placebo will be administered orally as per arms they have been assigned.
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-04-22
- Primary Completion
- 2025-09-29
- Completion
- 2025-09-29
Countries
- Germany
Study Locations
More Related Trials
-
A Study of ZT002 Injection in Participants With Overweight or Obesity
NCT06371326 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Participants With Obesity or Overweight With at Least One Weight-related Comorbidity
NCT06595238 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Examine Safety, Tolerability and Effect on Body Weight of Subcutaneous AC2307 in Obese or Overweight Subjects
NCT00785408 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of LY3437943 in Chinese Participants With Obesity Or Overweight
NCT05548231 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Test Different Doses of BI 456906 in Patients With Obesity
NCT03591718 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
NCT06845202 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Examine the Effect of Pramlintide on Body Weight and Its Safety and Tolerability in Obese Subjects
NCT00112021 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability and Pharmacokinetics of Multiple Doses of ZGN-433 in Obese Female Volunteers
NCT01028261 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Test How Well Different Doses of BI 1356225 Are Tolerated by Men and Women With Obesity or Overweight
NCT04447261 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy, Safety and Tolerability of AZD6234 in Participants Living With Overweight or Obesity With Type 2 Diabetes Who Are on a Stable Dose of GLP-1 Receptor Agonist
NCT06851858 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of DA-302168S Tablets in Overweight/Obese Subjects
NCT06953063 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of ZT002 Injection With Subjects With Overweight or Obesity
NCT07020884 ·Status: COMPLETED ·Phase: PHASE2
-
Phase Ib Clinical Study on the Efficacy and Safety of MDR-001 in Patients Who Are Obesity or Overweight
NCT07110766 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Safety Study to Evaluate BMS-830216 in Healthy Subjects
NCT00878020 ·Status: COMPLETED ·Phase: PHASE1
-
A Multiple Dose Study to Assess the Safety and Tolerability of BMS-963272 in Obese But Otherwise Healthy Adults
NCT04116632 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Zenoctil in Reducing Body Weight
NCT01423617 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Efficacy and Safety of MDR-001 in Subjects Who Are Obesity or Overweight
NCT06606483 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IBI362 in Overweight or Obesity Subjects
NCT04440345 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
DBRPC Study to Evaluate the Efficacy and Safety of IQP-AE-103 in Overweight and Moderately Obese Subjects
NCT04086797 ·Status: COMPLETED ·Phase: NA
-
An Investigational Drug Study in Obese (Considerably Overweight) Patients (0364-006)
NCT00109148 ·Status: COMPLETED ·Phase: PHASE2
-
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
NCT07339423 ·Status: RECRUITING ·Phase: PHASE3
-
Safety and Efficacy of Low Doses of V24343 in Obese Subjects
NCT00734201 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase III Study to Evaluate the Efficacy and Safety of MDR-001 in Adult Participants With Overweight or Obesity (MOBILE)
NCT07274137 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
A Study to Determine the Effects of TM30339 on Weight Loss in Obese Individuals.
NCT00746824 ·Status: TERMINATED ·Phase: PHASE2
-
A Multiple Dose Study Of PF-04620110 In Overweight And Obese, Otherwise Healthy Volunteers
NCT00959426 ·Status: COMPLETED ·Phase: PHASE1