Trial Outcomes & Findings for SMART Pilot Trial of Glycemic Screening Outreach (NCT NCT06915194)

NCT ID: NCT06915194

Last Updated: 2026-05-15

Results Overview

Receipt of hemoglobin A1c screening for dysglycemia

Recruitment status

COMPLETED

Study phase

Target enrollment

102 participants

Primary outcome timeframe

90 days

Results posted on

2026-05-15

Participant Flow

PCPs requested that we not enroll 12 potential participants, so while we recruited 113 participants only 102 received the intervention. Because this intervention was consistent with standard of care, we had IRB approval to waive informed consent. Therefore, we sent messages to all 102 individuals who were approved to participate by their PCP

Participant milestones

Participant milestones
Measure	Initial Text, Follow-up Text, Letter Participants are initially randomized to glycemic screening invitations by text, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by text. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Initial Portal, Follow-up Portal, Letter Participants are initially randomized to glycemic screening invitations by patient portal, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by patient portal. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Initial Text, Follow-up Portal, Letter Participants are initially randomized to glycemic screening invitations by text, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by patient portal. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Initial Portal, Follow-up Text, Letter Participants are initially randomized to glycemic screening invitations by patient portal, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by text. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Usual Care Patients do not receive any glycemic screening invitations
Overall Study STARTED	16	17	17	18	34
Overall Study Week 4 assessment	16	17	17	18	34
Overall Study Week 8 assessment	16	17	17	18	34
Overall Study COMPLETED	16	17	17	18	34
Overall Study NOT COMPLETED	0	0	0	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

SMART Pilot Trial of Glycemic Screening Outreach

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Initial Portal, Follow-up Portal, Letter n=17 Participants Participants are initially randomized to glycemic screening invitations by patient portal, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by patient portal. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Initial Text, Follow-up Portal, Letter n=17 Participants Participants are initially randomized to glycemic screening invitations by text, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by patient portal. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Initial Portal, Follow-up Text, Letter n=18 Participants Participants are initially randomized to glycemic screening invitations by patient portal, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by text. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Usual Care n=34 Participants Patients do not receive any glycemic screening invitations	Initial Text, Follow-up Text, Letter n=16 Participants Participants are initially randomized to glycemic screening invitations by text, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by text. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Total n=102 Participants Total of all reporting groups
Race/Ethnicity, Customized White, Non-Hispanic	10 Participants n=11 Participants	14 Participants n=9 Participants	11 Participants n=20 Participants	19 Participants n=186 Participants	10 Participants n=12 Participants	64 Participants n=12 Participants
Age, Categorical <=18 years	0 Participants n=11 Participants	0 Participants n=9 Participants	0 Participants n=20 Participants	0 Participants n=186 Participants	0 Participants n=12 Participants	0 Participants n=12 Participants
Age, Categorical Between 18 and 65 years	17 Participants n=11 Participants	16 Participants n=9 Participants	16 Participants n=20 Participants	31 Participants n=186 Participants	16 Participants n=12 Participants	96 Participants n=12 Participants
Age, Categorical >=65 years	0 Participants n=11 Participants	1 Participants n=9 Participants	2 Participants n=20 Participants	3 Participants n=186 Participants	0 Participants n=12 Participants	6 Participants n=12 Participants
Sex: Female, Male Female	6 Participants n=11 Participants	8 Participants n=9 Participants	8 Participants n=20 Participants	16 Participants n=186 Participants	10 Participants n=12 Participants	48 Participants n=12 Participants
Sex: Female, Male Male	11 Participants n=11 Participants	9 Participants n=9 Participants	10 Participants n=20 Participants	18 Participants n=186 Participants	6 Participants n=12 Participants	54 Participants n=12 Participants
Race/Ethnicity, Customized Asian	4 Participants n=11 Participants	3 Participants n=9 Participants	3 Participants n=20 Participants	5 Participants n=186 Participants	4 Participants n=12 Participants	19 Participants n=12 Participants
Race/Ethnicity, Customized White, Hispanic	2 Participants n=11 Participants	0 Participants n=9 Participants	3 Participants n=20 Participants	9 Participants n=186 Participants	1 Participants n=12 Participants	15 Participants n=12 Participants
Race/Ethnicity, Customized Black	1 Participants n=11 Participants	0 Participants n=9 Participants	1 Participants n=20 Participants	1 Participants n=186 Participants	1 Participants n=12 Participants	4 Participants n=12 Participants

PRIMARY outcome

Timeframe: 90 days

Receipt of hemoglobin A1c screening for dysglycemia

Outcome measures

Outcome measures
Measure	Initial Text, Follow-up Text, Letter n=16 Participants Participants are initially randomized to glycemic screening invitations by text, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by text. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Initial Portal, Follow-up Portal, Letter n=17 Participants Participants are initially randomized to glycemic screening invitations by patient portal, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by patient portal. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Initial Text, Follow-up Portal, Letter n=17 Participants Participants are initially randomized to glycemic screening invitations by text, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by patient portal. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Initial Portal, Follow-up Text, Letter n=18 Participants Participants are initially randomized to glycemic screening invitations by patient portal, and then if they are not screened within 30 days, then they are re-rerandomized to another glycemic screening invitation by text. If they are still not screened in another 30 days then they receive a mailed letter encouraging glycemic screening.	Usual Care n=34 Participants Patients do not receive any glycemic screening invitations
Hemoglobin A1c	6 Participants	6 Participants	9 Participants	7 Participants	9 Participants

SECONDARY outcome

Timeframe: 90 Days

Population: Two participants responded from the 4 intervention arms.

The survey contained 5 questions, in Likert response format, and possible total scores ranged from 0 - 24 , with higher scores indicating better satisfaction. 1. How did you feel about the messages recommending that you come in for a blood test to check your hemoglobin A1c (blood sugar) level - Likert responses (Very positive, positive, neutral, negative, very negative) 2. How clear were the messages recommending that you come in for a blood test to check your hemoglobin A1c (blood sugar) level - Likert responses (Very clear, somewhat clear, neutral, somewhat unclear, very unclear) 3. Did the messages affect the chances that you would get the hemoglobin A1c (blood sugar) level - Likert responses (Major effect, moderate effect, neutral, minor effect, no effect) 4. Did the messages cause you any anxiety or stress - Likert responses (To a great extent, somewhat, very little, not at all) 5. How concerned were you that the messages were from scammers not associated with