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Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure

NCT06914349 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 76

Last updated 2025-06-06

No results posted yet for this study

Summary

Aim: This randomized clinical study aims to compare occurrence of DGE in patients undergoing either antecolic or retrocolic gastrojejunostomy following pancreaticoduodenectomy.

Methods: Participants of this study will be patients undergoing pylorus preserving pancreaticoduodenectomy at the Surgical Department of the University Hospital of Larissa. Patients will be randomized to undergo either an antecolic or a retrocolic gastrojejunostomy and the occurrence of DGE will then be compared between the two groups. Individuals younger than 18 or older than 75 years old, as well as patients who do not consent to participate in this trial, will be excluded.

Expected results: Based on available literature, antecolic gastrojejunostomy may be related with a lower incidence of DGE, without a statistically significant difference between the two methods. We aim to show if one of the two methods of gastrointestinal reconstruction (antecolic versus retrocolic) affects DGE.

Conditions

  • Pancreatic Cancer Resectable
  • Pancreas Neoplasms

Interventions

PROCEDURE

Antecolic gastrojejunostomy

Gastrojejunostomy in front of the transverse colon

PROCEDURE

Retrocolic gastrojejunostomy

Gastrojejunostomy through the transverse mesocolon

Sponsors & Collaborators

  • University of Thessaly

    lead OTHER

Principal Investigators

  • Dimitrios Symeonidis · University of Thessaly

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-30
Primary Completion
2028-03-31
Completion
2029-03-31

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06914349 on ClinicalTrials.gov