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Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants

NCT06910709 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2026-04-02

No results posted yet for this study

Summary

The main objective of the study is to assess the safety and tolerability of AMG 378 as single or multiple doses in healthy participants.

Conditions

  • Healthy Volunteers

Interventions

DRUG

AMG 378

Oral tablet

DRUG

Placebo

Oral tablet

Sponsors & Collaborators

Principal Investigators

  • MD · Amgen

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-04-08
Primary Completion
2025-12-02
Completion
2025-12-02
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06910709 on ClinicalTrials.gov