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Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation

NCT06910293 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2025-06-10

No results posted yet for this study

Summary

The investigators aim is to investigate the brain's dynamic complexity across three phases of an ovarian stimulation cycle (basal, pre-OPU, mid-luteal), to observe the impact of externally administered hormones, and compare it with the corresponding phases of a natural menstrual cycle (early follicular, pre-ovulatory, mid-luteal) in the same woman. Brain activity patterns will be examined using resting-state fMRI in a sample of young, healthy, naturally cycling women.

Conditions

  • Neural Activity
  • Brain Function
  • Neurodynamics
  • Brain Connectivity

Interventions

DIAGNOSTIC_TEST

Functional Magnetic resonance imaging will be done on day 2 or 3 of the menstrual cycle, trigger-shot and egg retrieval.

Functional Magnetic resonance imaging will be done on day 2 or 3 of the menstrual cycle, trigger-shot and egg retrieval.

Sponsors & Collaborators

  • Khalifa University for Science and Technology

    collaborator OTHER

  • New York University Abu Dhabi

    collaborator UNKNOWN

  • ART Fertility Clinics LLC

    lead OTHER

Eligibility

Min Age
25 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-04-07
Primary Completion
2026-04-05
Completion
2026-12-05

Countries

  • United Arab Emirates

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06910293 on ClinicalTrials.gov