An Early Access Program Guideline to Provide Access to Retifanlimab (INCMGA00012) Together With Carboplatin and Paclitaxel for Squamous Carcinoma of the Anal Canal (SCAC)
NCT06910137 · Status: AVAILABLE · Type: EXPANDED_ACCESS
Last updated 2026-01-08
Summary
To provide retifanlimab, on a reactive basis, to adult patients with squamous carcinoma of the anal canal in combination with carboplatin and paclitaxel and who are considered ineligible for other therapeutic options including clinical trials.
Conditions
Interventions
- DRUG
-
Administered intravenous as defined in the protocol.
Sponsors & Collaborators
- lead INDUSTRY
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
More Related Trials
-
Investigating Cabozantinib in Patients With Refractory Metastatic Colorectal Cancer
NCT03542877 ·Status: COMPLETED ·Phase: PHASE2
-
Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS)
NCT03944252 ·Status: UNKNOWN ·Phase: PHASE2
-
Capecitabine, Panitumumab, and Radiation Therapy With or Without Irinotecan Hydrochloride in Treating Patients Undergoing Surgery for Localized Rectal Cancer
NCT00967655 ·Status: UNKNOWN ·Phase: PHASE2
-
Paclitaxel Cationic Liposome (Hepatic Arterial Infusion) in Combination With Systemic Therapy as First-Line Treatment in Colorectal Liver Metastases
NCT07117435 ·Status: RECRUITING ·Phase: PHASE1
-
Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer
NCT03386500 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum
NCT00346099 ·Status: WITHDRAWN ·Phase: PHASE2
-
Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine As Conversion Therapy of Locally Advanced Colorectal Cancer
NCT06405139 ·Status: RECRUITING ·Phase: PHASE2
-
Panitumumab and Irinotecan as Third-Line Therapy in Treating Patients With Metastatic Colorectal Cancer
NCT00655499 ·Status: COMPLETED ·Phase: PHASE2
-
Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer
NCT03711058 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer
NCT04117945 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Palbociclib and Cetuximab in Metastatic Colorectal Cancer
NCT03446157 ·Status: COMPLETED ·Phase: PHASE2
-
Pixatimod (PG545) Plus Nivolumab in PD-1 Relapsed/Refractory Metastatic Melanoma and NSCLC and With Nivolumab and Low-dose Cyclophosphamide in MSS Metastatic Colorectal Carcinoma (mCRC)
NCT05061017 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors
NCT02703571 ·Status: TERMINATED ·Phase: PHASE1
-
Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)
NCT06462183 ·Status: RECRUITING ·Phase: PHASE1
-
An Investigational Immunotherapy Study of Nivolumab With Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Colorectal Cancer That Has Spread
NCT03414983 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer
NCT03657641 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients
NCT04444921 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer
NCT00686166 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer
NCT04607421 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
I-MVAC +/- Panitumumab as First-line Treatment of Advanced Urothelial Carcinoma Without H-Ras Nor K-Ras Mutations
NCT02818725 ·Status: COMPLETED ·Phase: PHASE3
-
Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy
NCT00336856 ·Status: COMPLETED ·Phase: PHASE2
-
First-Line FOLFOX-Bevacizumab for Advanced Colorectal Cancer With Wild-Type Ras
NCT01057017 ·Status: TERMINATED ·Phase: PHASE2
-
Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and/or Lung
NCT00557102 ·Status: COMPLETED ·Phase: PHASE2
-
Total Neoadjuvant Therapy Versus Standard Therapy of Locally Advanced Rectal Cancer With High Risk Factors for Failure
NCT04679597 ·Status: COMPLETED
-
Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer
NCT02314169 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2