Dapagliflozin for Long COVID Syndrome
NCT06907251 · Status: NOT_YET_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 192
Last updated 2026-05-01
Summary
This is a randomized, placebo-controlled study. Patients with long COVID will be randomized to receive dapagliflozin or placebo for 12 months.
Conditions
- COVID - 19
- Long COVID Syndrome
- SARS CoV-2
Interventions
- DRUG
-
Dapagliflozin (DAPA)
Dapagliflozin 10mg orally once a day for 12 months
- DRUG
-
Participants will receive a matching placebo taken once daily by mouth for 12 months.
Sponsors & Collaborators
-
Ottawa Heart Institute Research Corporation
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-01
- Primary Completion
- 2028-06-30
- Completion
- 2029-06-30
Countries
- Canada
Study Locations
More Related Trials
-
Dapagliflozin Effects on Cardiometabolic Outcomes in Patients With an Acute Heart Attack.
NCT04564742 ·Status: COMPLETED ·Phase: PHASE3
-
Dapagliflozin (DAPA) Effects in HFpEF
NCT04730947 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Dapagliflozin on Electrocardiographic Parameters in Type 2 Diabetes Patients: DAPA - ECG Study
NCT06721442 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Dapagliflozin on Submaximal Exercise Tolerance in Heart Failure
NCT04956809 ·Status: COMPLETED ·Phase: PHASE2
-
DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction
NCT05764057 ·Status: RECRUITING ·Phase: PHASE3
-
Dapagliflozin in the Prevention of Post-Coronary Angioplasty Acute Kidney Injury
NCT05435235 ·Status: SUSPENDED ·Phase: PHASE4
-
DETERMINE-preserved - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Preserved Ejection Fraction
NCT03877224 ·Status: COMPLETED ·Phase: PHASE3
-
Sodium-Glucose Cotransporter-2 Inhibitor for Acute Cardiorenal Syndrome: A Feasibility Study
NCT06111768 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure
NCT03036124 ·Status: COMPLETED ·Phase: PHASE3
-
DETERMINE-reduced - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Reduced Ejection Fraction
NCT03877237 ·Status: COMPLETED ·Phase: PHASE3
-
Dapagliflozin in the Treatment of Heart Failure
NCT05727423 ·Status: ACTIVE_NOT_RECRUITING
-
The Effect of Early Administration of Dapagliflozin in STEMI Patients With LV Systolic Dysfunction
NCT05045274 ·Status: UNKNOWN ·Phase: NA
-
Dapagliflozin in Systemic Right Ventricle (DAPA-SERVE)
NCT05717257 ·Status: UNKNOWN ·Phase: PHASE4
-
Dapagliflozin at Discharge on Hospital Heart Failure Readmission
NCT04249778 ·Status: COMPLETED ·Phase: PHASE4
-
Stratified Treatment to Ameliorate Diastolic Left Ventricular Stiffness in Heart Failure With Preserved Ejection Fraction
NCT04475042 ·Status: UNKNOWN ·Phase: PHASE2
-
The Effect of Dapagliflozin on Patients With Cardiomyopathy
NCT07076615 ·Status: RECRUITING ·Phase: PHASE4
-
Dapagliflozin Effects on Mayor Adverse Cardiovascular Events in Patients With Acute Myocardial Infarction (DAPA-AMI)
NCT04717986 ·Status: COMPLETED ·Phase: NA
-
Protecting With ARNI Against Cardiac Consequences of Coronavirus Disease 2019
NCT04883528 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Cardiometabolic Effects of Dapagliflozin in Heart Failure With Reduced or Mildly Reduced Ejection Fraction
NCT05420285 ·Status: UNKNOWN ·Phase: PHASE2
-
Effects of Dapagliflozin on EChOcardiographic Measures of CarDiac StructurE and Function in Patients with CKD
NCT05359263 ·Status: RECRUITING ·Phase: PHASE2
-
Empagliflozin on Patients With Preserved Heart Failure
NCT07112274 ·Status: COMPLETED ·Phase: NA
-
Dapagliflozin on Hypotensive Heart Failure Patients After Sacubitril/Valsartan Therapy
NCT04575675 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Dapagliflozin in Myocardial Fibrosis and Ventricular Function in Patients With a ST-segment Elevation Myocardial Infarction
NCT06619600 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Effect of Dapagliflozin on Myocardial and Renal Function Following Aortic Valve Stenosis Intervention
NCT05241431 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
ISGLT2 in Patients Without DM With Acute MI
NCT06903754 ·Status: COMPLETED