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A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV Infection

NCT06903338 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 124

Last updated 2026-04-08

No results posted yet for this study

Summary

This is a multicenter, open label, randomized Phase 3 clinical study to evaluate the efficacy and safety of the combination of tobevibart + elebsiran for the treatment of chronic hepatitis delta in comparison to delayed treatment.

Conditions

  • Viral Hepatitis

Interventions

DRUG

Tobevibart

Tobevibart administered by subcutaneous injection

DRUG

Elebsiran

Elebsiran administered by subcutaneous injection

Sponsors & Collaborators

  • Vir Biotechnology, Inc.

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-12
Primary Completion
2026-12-31
Completion
2031-05-31
FDA Drug
Yes

Countries

  • United States
  • Canada
  • Georgia
  • Germany
  • Moldova
  • New Zealand
  • Pakistan
  • Romania
  • Ukraine
  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06903338 on ClinicalTrials.gov