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Radiographic Evaluation in Alveolar Preservation Using Platelet-rich Fibrin. Randomized Controlled Trial

NCT06900036 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2025-03-28

No results posted yet for this study

Summary

This randomized controlled trial is designed to assess the use of platelet-rich fibrin (PRF), a biomaterial derived from a participant's own blood, in alveolar ridge preservation following premolar extraction for orthodontic purposes. Participants aged 17 to 38 years requiring premolar extractions will be randomly assigned to receive either PRF application or natural healing without intervention. Cone beam computed tomography (CBCT) will be used to evaluate changes in alveolar bone dimensions and density at 30 and 120 days post-extraction. Measurements will be taken at standardized vertical levels (1 mm, 3 mm, and 5 mm apical to the crest) to analyze bone height, width, and density over time.

Conditions

  • Alveolar Bone Resorption
  • Preserving the Alveolar Ridge

Interventions

PROCEDURE

Platelet-Rich Fibrin (PRF) Application for Alveolar Preservation

This intervention involves the application of platelet-rich fibrin (PRF) in the extraction socket following premolar extraction to assess its effectiveness in alveolar bone preservation. PRF is a biological autologous material derived from the patient's own blood, promoting bone regeneration, wound healing, and tissue repair.

Sponsors & Collaborators

  • Universidad Católica de Cuenca

    lead OTHER

Principal Investigators

  • ROCIO MAGDALENA MOLINA BARAHONA, Doctor of Dental Surgery (DDS) · Universidad Católica de Cuenca

  • RENATA A AVECILLAS RODAS, Doctor of Dental Surgery (DDS) · Universidad Católica de Cuenca

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
17 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-03-01
Primary Completion
2023-09-28
Completion
2024-11-20

Countries

  • Ecuador

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06900036 on ClinicalTrials.gov