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Impact of IIT-SIT on Dengue Clusters

NCT06894901 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 900

Last updated 2025-03-25

No results posted yet for this study

Summary

This randomized controlled trial aims to evaluate the efficacy of Wolbachia-infected male mosquitoes combined with sterile insect technique (IIT-SIT) to mitigate active dengue transmission in Singapore.

Conditions

  • Dengue

Interventions

BIOLOGICAL

Biological (Male Wolbachia-infected Aedes aegypti)

Releases of male Wolbachia-infected Aedes aegypti mosquitoes

Sponsors & Collaborators

  • Ministry of Health, Singapore

    collaborator OTHER_GOV

  • National Environment Agency, Singapore

    lead OTHER_GOV

Principal Investigators

  • Lee Ching Ng Group Director (Environmental Health Institute), PhD · Environmental Health Institute

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-20
Primary Completion
2027-07-20
Completion
2028-01-20

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06894901 on ClinicalTrials.gov