A Study of Bimagrumab Alone (LY3985863) and Bimagrumab With Tirzepatide (LY900042) in Healthy Participants
NCT06890611 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 125
Last updated 2025-10-09
Summary
The main purpose of this study is to evaluate the body concentration of different forms of bimagrumab, administered alone or with tirzepatide. Participation in the study will last about 4.5 months, including screening and follow-up.
Conditions
- Healthy
Interventions
- DRUG
-
Bimagrumab
Administered SC
- DRUG
-
Administered SC
- DRUG
-
Bimagrumab + Tirzepatide Coformulation
Administered SC
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) · Eli Lilly and Company
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 64 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-03-25
- Primary Completion
- 2025-09-26
- Completion
- 2025-09-26
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or Obese
NCT05616013 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight
NCT04657003 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of LY3298176 (Tirzepatide) For the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
NCT06047548 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of LY3841136 in Overweight and Obese Participants
NCT06345066 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or Obesity
NCT06916065 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide
NCT04407234 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity
NCT05933499 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Tirzepatide in Overweight and Very Overweight Participants
NCT04311411 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY3457263 in Obese Participants
NCT05582096 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity
NCT06037252 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
NCT04657016 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight
NCT04184622 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
NCT06662383 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of Tirzepatide (LY3298176) in Healthy Participants
NCT03375463 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Measure Energy Expenditure and Food Intake in Participants With Obesity Using Tirzepatide
NCT04081337 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study Looking at Similarity Between Tirzepatide Versions for Different Injection Devices
NCT05810597 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss
NCT04660643 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Pharmacokinetics and Efficacy of Bimagrumab in Overweight and Obese Patients With Type 2 Diabetes
NCT03005288 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes
NCT03311724 ·Status: COMPLETED ·Phase: PHASE2
-
A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight
NCT06962280 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
NCT06143956 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight
NCT06914895 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of LY3841136 in Japanese Participants With Obesity or Overweight
NCT06297616 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Tirzepatide (LY3298176) in Participants With Obesity Disease
NCT04844918 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Tirzepatide (LY3298176) Compared to Dulaglutide in Participants With Type 2 Diabetes
NCT03861052 ·Status: COMPLETED ·Phase: PHASE3