Prediction of LVAR and MACE in STEMI Though Plasma Multiomics Analysis
NCT06885619 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2026-05-12
Summary
To identify plasma multi-omics biomarkers that predict left ventricular adverse remodeling (LVAR) and major adverse cardiovascular events (MACE) in patients with acute ST-segment elevation myocardial infarction, and to investigate the molecular pathways linked to LVAR and MACE.
Conditions
- Left Ventricular Remodeling
- Plasma Multi-Omics
- Acute ST-segment Elevation Myocardial Infarction
- Immunomics
- Major Adverse Cardiovascular Events
Interventions
- OTHER
-
Diagnostic Test: echocardiography and blood collection
Blood samples were collected from all patients at enrollment (within 24 hours after primary PCI), at days 3-5, and at months 1, 3, and 6 after enrollment. Echocardiography was performed at enrollment (baseline, within 24-48 hours after admission), and at months 1, 3, and 6 after enrollment.
Sponsors & Collaborators
-
Beijing Jishuitan Hospital
collaborator OTHER -
Institute of Biophysics, Chinese Academy of Sciences
collaborator UNKNOWN -
Beijing Anzhen Hospital
lead OTHER
Principal Investigators
-
Xu Wang, Dr. · Beijing Anzhen hospital, Capital Mediacl University.
-
Tanxi Cai, Dr. · Institute of Biophysics, Chinese Academy of Sciences
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-05-01
- Primary Completion
- 2027-12-31
- Completion
- 2027-12-31
Countries
- China
Study Locations
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