A Clinical Study to Evaluate Enlicitide (MK-0616) Formulations in Healthy Adult Participants (MK-0616-035)
NCT06880874 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2025-06-15
Summary
The goal of the study is to learn what happens to different forms of enlicitide medications in a healthy person's body over time. Researchers will compare the amount of enlicitide in the healthy person's body over time when enlicitide is given in different formulations.
Conditions
- Healthy
Interventions
- DRUG
-
Oral Tablet
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Medical Director · Merck Sharp & Dohme LLC
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-04-02
- Primary Completion
- 2025-05-16
- Completion
- 2025-05-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Evaluate the Bioavailability Between 2 BMS-986141 Formulations in Healthy Participants
NCT03035734 ·Status: WITHDRAWN ·Phase: PHASE1
-
Phase 1 BA Study, Single Center With Healthy Volunteers
NCT00870948 ·Status: COMPLETED ·Phase: PHASE1
-
A Pharmacokinetic Study of Baricitinib in Participants With Liver Disease
NCT01870388 ·Status: COMPLETED ·Phase: PHASE1
-
Relative Bioavailability of Evobrutinib Tablet Batches
NCT07214922 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult Participants
NCT05852340 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Relative Bioavailability of Gilteritinib Following a Single Dose of Gilteritinib Mini-tablet Oral Suspension and Gilteritinib Mini-tablets Compared to a Single Dose of Gilteritinib Tablet in Healthy Subjects
NCT03964038 ·Status: COMPLETED ·Phase: PHASE1
-
Study Comparing 2 New Formulations of HKI-272 in Healthy Adult Subjects
NCT00498745 ·Status: COMPLETED ·Phase: PHASE1
-
Relative Bioavailability (rBA) of Evobrutinib Intended Commercial and Clinical Tablets, and Effect of Food on Intended Commercial Tablets
NCT04314024 ·Status: COMPLETED ·Phase: PHASE1
-
A Bioavailability Study of MIV-711 Oral Formulations in Healthy Volunteers
NCT03443453 ·Status: COMPLETED ·Phase: PHASE1
-
Study Comparing Pharmacokinetics of Different Formulations of Evobrutinib in Healthy Participants
NCT05245396 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Baricitinib and Simvastatin in Healthy Participants
NCT01960140 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Baricitinib in Healthy Japanese Participants
NCT02263911 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Two Dosage Forms of LY2886721 in Healthy Participants
NCT01775904 ·Status: COMPLETED ·Phase: PHASE1
-
Bioavailability of Enasidenib (CC-90007) Sprinkle Formulation Relative to the Reference Tablet Formulation and Effect of Food on the Pharmacokinetics of Sprinkle Formulation in Healthy Adults
NCT04310527 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Baricitinib in Healthy Participants
NCT03212638 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Compare Two Forms of LY2608204 in Healthy People
NCT01313286 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Merestinib (LY2801653) in Healthy Participants
NCT02779738 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess Relative Bioavailability and Food Effect of ABBV-668 Extended-Release Formulations in Adult Participants
NCT06477926 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics and Bioavailability Comparison of Two Different Formulations of MNTX Tablets
NCT01366352 ·Status: COMPLETED ·Phase: PHASE1
-
A Performance and Bioavailability Study of Entrectinib in Healthy Volunteers.
NCT03961100 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY3039478 in Healthy Participants
NCT02659865 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY2409021 in Healthy Participants
NCT02217618 ·Status: COMPLETED ·Phase: PHASE1
-
An Investigational Study to Evaluate Experimental Medication BMS-986165 Given as a Tablet and Solution in Healthy Male Participants
NCT03739788 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Healthy People to Test How 2 Different Doses of BI 1291583 Are Taken up in the Body When Given in 3 Different Formulations
NCT06631417 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1 Absolute Bioavailability Study For Oral Crizotinib In Healthy Volunteers
NCT01168934 ·Status: COMPLETED ·Phase: PHASE1