The Evaluation of Molecular Markers From PRedittivI DNA of Clinical Outcomes in Patients With UROthelial Tumor
NCT06863844 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 210
Last updated 2025-03-07
Summary
The genetic characterization of urothelial tumor disease has brought to light important information about the biology of the disease. The evaluation of molecular DNA markers on tumor tissue could be an approach able to provide important information on the possible aggressiveness of the disease and the sensitivity/resistance profile to drugs commonly adopted in the advanced stage. The main objective of this study is to identify specific molecular profiles from DNA capable of predicting the clinical course of the disease and the possible sensitivity/resistance of the disease to systemic treatments
Conditions
- Urothelial Neoplasm
Sponsors & Collaborators
-
IRCCS Azienda Ospedaliero-Universitaria di Bologna
lead OTHER
Principal Investigators
-
Francesco Massari, MD · IRCCS Azienda Ospedaliero-Universitaria di Bologna
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-03-01
- Primary Completion
- 2025-03-31
- Completion
- 2025-03-31
Countries
- Italy
Study Locations
More Related Trials
-
"Principle Test" for Isolation and Characterization of Circulating Cancer Cells (CTC)-CXCR4+.
NCT05818865 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries
NCT05769517 ·Status: RECRUITING
-
Development of Urologic Registry for Personalized Medicine in Patients With Urological Malignancy by Analyzing Circulating Tumor DNA
NCT04197414 ·Status: RECRUITING
-
Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy
NCT06290856 ·Status: TERMINATED
-
Assessment of the Minimal Residual Disease in Ovarian Cancer From Circulating Tumor DNA and Immune Repertoire
NCT03614689 ·Status: ACTIVE_NOT_RECRUITING
-
Mutational Oncology in Clinical Practice
NCT06020625 ·Status: RECRUITING ·Phase: NA
-
Analysis of Circulating Tumor Markers in the Blood (ALCINA)
NCT02866149 ·Status: COMPLETED ·Phase: NA
-
ctDNA-MRD Monitoring After Resection in Gastric Cancer
NCT06893133 ·Status: RECRUITING
-
Analysis of Molecular Biomarkers in Periocular Adnexal Tumours
NCT06080009 ·Status: RECRUITING ·Phase: NA
-
Molecular Profiling in Prostate Cancer
NCT04983628 ·Status: UNKNOWN
-
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
NCT04354064 ·Status: RECRUITING
-
Potential Clinical Utilities of Circulating Tumor DNA in Advanced HER2 Negative Gastric Cancer
NCT05513144 ·Status: UNKNOWN
-
Development of New Methodologies and Innovative Tools for the diagnoSi and Therapeutic Treatment of uMAni Epithelial Tumors
NCT06939049 ·Status: COMPLETED
-
Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease
NCT00026884 ·Status: RECRUITING
-
Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas
NCT03194347 ·Status: COMPLETED
-
Real-time Monitoring of Concentration and Size Variations of Circulating Plasma Free DNA to Predict Early Response to Immunotherapies in Patients With Different Types of Cancer.
NCT05083494 ·Status: UNKNOWN
-
Blood Cell RNA-Based Cancer Detection
NCT05839834 ·Status: RECRUITING
-
Use of Ctdna in Patients With Gastrointestinal Tract Tumors
NCT06202131 ·Status: RECRUITING
-
A Cohort Study of Hereditary Ovarian Cancer Risk Prediction Models and Pathogenesis Exploration
NCT06564428 ·Status: RECRUITING
-
Implementation of the Methylome in the Characterization of Solid Tumors
NCT07268066 ·Status: RECRUITING
-
Urine DNA Methylation Detection for Hematuria Evaluation
NCT06427993 ·Status: NOT_YET_RECRUITING
-
Urinary Proteomic Assessment of Ovarian Malignancy and Disease Progression
NCT06760923 ·Status: RECRUITING
-
DNA Analysis in Influencing Response to Rituximab in Samples From Patients With Follicular Lymphoma Treated on ECOG-E4402
NCT01406782 ·Status: COMPLETED
-
Prospective Multicenter Study in Patients With a Tumor Benign Ovarian Presumed on the Use of Algorithms Such as Roma and RMI and Tumor Markers Such as CA125 and HE4
NCT02326064 ·Status: COMPLETED
-
Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria
NCT06469229 ·Status: NOT_YET_RECRUITING