Chemoradiotherapy in Elderly Patients with Locally Advanced Pancreatic Cancer (70+).
NCT06844773 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 36
Last updated 2025-02-25
Summary
The goal of this observational study is to learn about the therapeutic effects of chemoradiotherapy for older adults (age 70-85) with locally advanced pancreatic cancer. The main question it aims to answer is:
Does chemoradiotherapy represent an effective and safe treatment for older participants without radical surgery? Participants will sequentially receive combined chemotherapy followed by concurrent chemoradiotherapy and subsequent maintenance therapy.
Conditions
- Unresectable Locally Advanced Pancreatic Cancer
Sponsors & Collaborators
-
Shanghai Zhongshan Hospital
lead OTHER
Eligibility
- Min Age
- 70 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-28
- Primary Completion
- 2027-02-28
- Completion
- 2028-02-29
Countries
- China
Study Locations
More Related Trials
-
A Study of Chemoradiotherapy Using Gem Plus Nab-paclitaxel for Pancreatic Cancer
NCT02272738 ·Status: COMPLETED ·Phase: PHASE1
-
Hypofractionated Radiotherapy +Chemotherapy+ Camrelizumab as Neoadjuvant Therapy for Pancreatic Cancer
NCT06435260 ·Status: RECRUITING ·Phase: PHASE2
-
Borderline Resectable Pancreatic Cancer Neoadjuvant Chemoradiotherapy Clinicaltrial-1
NCT03777462 ·Status: UNKNOWN ·Phase: PHASE2
-
Combination of SBRT With Sequential S-1 for Treating Locally Advanced Pancreatic Cancer
NCT02704143 ·Status: COMPLETED ·Phase: NA
-
An Open-label, Multicenter, Prospective Study of Irreversible Electroporation (Nano Knife) Combined With Radiotherapy and Chemotherapy in Patients With Locally Advanced Pancreatic Cancer
NCT04310553 ·Status: UNKNOWN ·Phase: NA
-
Stereotactic Centralized Ablative Radiotherapy for Locally Advanced Pancreatic Cancer: A Single-Arm Phase I Safety and Feasibility Study
NCT07173374 ·Status: SUSPENDED ·Phase: PHASE1
-
Nab-Paclitaxel and Gemcitabine Plus Camrelizumab and Radiotherapy for Locally Advanced Pancreatic Adenocarcinoma
NCT04365049 ·Status: UNKNOWN
-
First-line Regimen With QL1706 Plus Chemo ± Bev in PDAC Patients
NCT06313970 ·Status: RECRUITING ·Phase: PHASE2
-
YL-13027 and/or HY-0102 Combined With AG Regimen Chemotherapy for Metastatic Pancreatic Cancer
NCT06662669 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Evaluate the Safety and Efficacy of PRRT With 177Lu-EB-FAPI in Patients With Advanced Cholopancreatic Tumors
NCT06081322 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of Immunotherapy Combined With Chemotherapy in Locally Advanced and Metastatic Pancreatic Cancer
NCT04324307 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
IORT Followed by CCRT or SBRT for Locally Advanced Pancreatic Cancer
NCT02734680 ·Status: UNKNOWN ·Phase: NA
-
QL1706 Plus Chemotherapy With AG Regime as First-line Treatment of Advanced PDAC
NCT06750861 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
AG Combined With Cadonilimab Sequential Short-course Radiotherapy in the Treatment of Locally aPDAC
NCT06472037 ·Status: RECRUITING ·Phase: PHASE2
-
Randomized Controlled Trial of Gemcitabine Combined With 125I Brachytherapy
NCT00644618 ·Status: COMPLETED ·Phase: PHASE3
-
Chemoradiation With Gemcitabine in Combination With Panitumumab for Patients With Locally Advanced Pancreatic Cancer
NCT01175733 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Evaluation of an Early Radiomic Signature in Patients With Metastatic Pancreatic Adenocarcinoma Treated With First-line Chemotherapy
NCT07243288 ·Status: ACTIVE_NOT_RECRUITING
-
Ganitumab and Gemcitabine Hydrochloride Followed by Radiation Therapy, Ganitumab, Capecitabine, and Maintenance Therapy in Treating Patients With Locally Advanced Cancer of the Pancreas
NCT01298401 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Low-Dose Fractionated Radiotherapy in Patients With Locally Advanced Metastatic Pancreatic Cancer
NCT00761345 ·Status: COMPLETED ·Phase: PHASE1
-
Split-course SBRT for Borderline Resectable and Locally Advanced Pancreatic Cancer
NCT04289792 ·Status: UNKNOWN ·Phase: PHASE2
-
Carbon Ion RT for Locally Advanced Pancreatic Cancer
NCT04592861 ·Status: TERMINATED ·Phase: PHASE3
-
Adebrelimab and Chidamide for Pancreatic Cancer
NCT06584227 ·Status: RECRUITING ·Phase: PHASE2
-
The Transformation of Locally Advanced Pancreatic Cancer.
NCT04723030 ·Status: UNKNOWN ·Phase: PHASE2
-
Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA
NCT07291063 ·Status: RECRUITING
-
Carbon Ion Radiotherapy for Locally Advanced Pancreatic Cancer
NCT04082455 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA