Investigation of Different Rehabilitation Approaches in Older Adults With Mild Cognitive Impairment

Summary

This randomized controlled trial aims to comparatively examine whether cognitive training and hand exercise training provided to older adults with mild cognitive impairment (MCI) have an impact on their cognitive functions, hand skills, grip strength, activities of daily living, dual task performance, and interactions. Based on the study's objectives, the following hypotheses were formulated:

* Hypothesis 1: Cognitive training has an effect on cognitive functions in older adults with MCI.
* Hypothesis 2: Cognitive training has an effect on dual-task performance in older adults with MCI.
* Hypothesis 3: Cognitive training has an effect on hand skills in older adults with MCI.
* Hypothesis 4: Resistance based hand exercises and functional task-oriented hand exercise training have an effect on cognitive functions in older adults with MCI.
* Hypothesis 5: Resistance based hand exercises and functional task-oriented hand exercise training have an effect on dual-task performance in older adults with MCI.
* Hypothesis 6: Resistance-based hand exercises and functional task-oriented hand exercise training have an effect on hand skills in older adults with MCI.

In this study, two different exercise interventions were applied to two experimental groups of individuals with mild cognitive impairment, while the control group did not receive any intervention. The first experimental group (Hand Exercise Group, HEG) and the second experimental group (Cognitive Training Group, CTG) underwent training administered by a physiotherapist three times per week for eight weeks.

To ensure assessor blinding, pre- and post-intervention assessments of the participants were conducted by an independent expert physiotherapist who was not involved in the study. The sociodemographic characteristics of the participants were collected using a data collection form. Cognitive functions were assessed with the Montreal Cognitive Assessment (MoCA); hand dominance was determined using the Edinburgh Handedness Inventory (EHI); hand dexterity was evaluated with the Nine-Hole Peg Test (NHPT); grip strength was measured using a hand dynamometer; motor-motor dual task performance (MMDTP) and motor-cognitive dual task performance (MCDTP) were assessed using a stopwatch; activities of daily living were evaluated with the Manual Ability Measurement-36, (MAM-36); and dual task interaction (DTI) was calculated using the following formula: DTI = (Single Task Performance - Dual Task Performance) / Single Task Performance × 100%.

Conditions

• Mild Cognitive Impairment (MCI)
• Geriatric

Interventions

OTHER

Resistance based hand exercises and functional task-oriented hand exercise

The interventions for HEG were administered by a physiotherapist over a period of eight weeks, with three sessions conducted each week.

OTHER

Cognitive training

The interventions for CTG were administered by a physiotherapist over a period of eight weeks, with three sessions conducted each week.

Sponsors & Collaborators

• Uşak University

  lead OTHER

Principal Investigators

• Kevser Gursan, Dr. · Uşak University

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

65 Years

Max Age

89 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2022-02-01

Primary Completion

2023-02-01

Completion

2023-02-01

Countries

• Turkey (Türkiye)

Study Locations