Trial Outcomes & Findings for the Effect of Reflexology in Migraine Patients (NCT NCT06828315)
NCT ID: NCT06828315
Last Updated: 2026-03-04
Results Overview
Pain intensity was assessed using the Visual Analog Scale (VAS) for Pain. The Visual Analog Scale is a unidimensional measure of perceived pain intensity. It consists of a 10-centimeter horizontal line anchored by two descriptors: "no pain" (0) and "worst imaginable pain" (10). Participants mark a point on the line corresponding to their perceived pain intensity, resulting in a score ranging from 0 to 10. Higher scores indicate greater pain severity and represent a worse outcome. Lower scores indicate less pain and represent a better outcome.
COMPLETED
NA
78 participants
At the end of the 5-week intervention
2026-03-04
Participant Flow
Participant milestones
| Measure |
Experimental Group
reflexology was applied to the experimental group
Reflexology: Reflexology is a practice based on the fact that the organs in the body are connected to the reflex areas in the hands and feet.
|
Control Group
reflexology was not applied to the control group
|
|---|---|---|
|
Pre-Intervention (Baseline)
STARTED
|
39
|
39
|
|
Pre-Intervention (Baseline)
COMPLETED
|
39
|
39
|
|
Pre-Intervention (Baseline)
NOT COMPLETED
|
0
|
0
|
|
Post-Intervention (At the End of Week 5)
STARTED
|
39
|
39
|
|
Post-Intervention (At the End of Week 5)
COMPLETED
|
39
|
39
|
|
Post-Intervention (At the End of Week 5)
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Race and Ethnicity were not collected from any participant.
Baseline characteristics by cohort
| Measure |
Experimental Group
n=39 Participants
reflexology was applied to the experimental group
Reflexology: Reflexology is a practice based on the fact that the organs in the body are connected to the reflex areas in the hands and feet.
|
Control Group
n=39 Participants
reflexology was not applied to the control group
|
Total
n=78 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
42.76 Year
STANDARD_DEVIATION 12.23 • n=39 Participants
|
38.41 Year
STANDARD_DEVIATION 10.63 • n=39 Participants
|
40.58 Year
STANDARD_DEVIATION 11.59 • n=78 Participants
|
|
Sex: Female, Male
Female
|
25 Participants
n=39 Participants
|
24 Participants
n=39 Participants
|
49 Participants
n=78 Participants
|
|
Sex: Female, Male
Male
|
14 Participants
n=39 Participants
|
15 Participants
n=39 Participants
|
29 Participants
n=78 Participants
|
|
Race and Ethnicity Not Collected
|
—
|
—
|
0 Participants
Race and Ethnicity were not collected from any participant.
|
|
Baseline Pain Intensity (Visual Analog Scale)
|
7.26 Score (range 0-10)
STANDARD_DEVIATION 1.48 • n=39 Participants
|
7.59 Score (range 0-10)
STANDARD_DEVIATION 1.25 • n=39 Participants
|
7.42 Score (range 0-10)
STANDARD_DEVIATION 1.37 • n=78 Participants
|
|
Baseline Fatigue Severity
|
43.77 Score (9-63)
STANDARD_DEVIATION 5.11 • n=39 Participants
|
43.10 Score (9-63)
STANDARD_DEVIATION 5.73 • n=39 Participants
|
43.43 Score (9-63)
STANDARD_DEVIATION 5.41 • n=78 Participants
|
|
Baseline Migraine-Specific Quality of Life
|
68.15 Score (15-105)
STANDARD_DEVIATION 8.27 • n=39 Participants
|
67.59 Score (15-105)
STANDARD_DEVIATION 6.01 • n=39 Participants
|
67.87 Score (15-105)
STANDARD_DEVIATION 7.18 • n=78 Participants
|
PRIMARY outcome
Timeframe: At the end of the 5-week interventionPain intensity was assessed using the Visual Analog Scale (VAS) for Pain. The Visual Analog Scale is a unidimensional measure of perceived pain intensity. It consists of a 10-centimeter horizontal line anchored by two descriptors: "no pain" (0) and "worst imaginable pain" (10). Participants mark a point on the line corresponding to their perceived pain intensity, resulting in a score ranging from 0 to 10. Higher scores indicate greater pain severity and represent a worse outcome. Lower scores indicate less pain and represent a better outcome.
Outcome measures
| Measure |
Experimental Group
n=39 Participants
reflexology was applied to the experimental group
Reflexology: Reflexology is a practice based on the fact that the organs in the body are connected to the reflex areas in the hands and feet.
|
Control Group
n=39 Participants
reflexology was not applied to the control group
|
|---|---|---|
|
Visual Analog Scale (VAS)
|
4.15 Score (0-10)
Standard Deviation 1.63
|
7.46 Score (0-10)
Standard Deviation 1.48
|
PRIMARY outcome
Timeframe: At the end of the 5-week interventionThe Fatigue Severity Scale (FSS) will be used to evaluate changes in participants' fatigue levels. The FSS consists of nine items scored from 1 to 7, with higher scores indicating greater fatigue severity. The total score ranges from a minimum of 9 to a maximum of 63.
Outcome measures
| Measure |
Experimental Group
n=39 Participants
reflexology was applied to the experimental group
Reflexology: Reflexology is a practice based on the fact that the organs in the body are connected to the reflex areas in the hands and feet.
|
Control Group
n=39 Participants
reflexology was not applied to the control group
|
|---|---|---|
|
Fatigue Severity Scale (FSS)
|
32.97 Score (9-63)
Standard Deviation 6.74
|
42.28 Score (9-63)
Standard Deviation 6.39
|
PRIMARY outcome
Timeframe: At the end of the 5-week intervention24-Hour Migraine-Specific Quality of Life Questionnaire (24 h MQoLQ) will assess changes in migraine-specific quality of life. It includes five subscales: Migraine Symptoms, Emotions and Concerns, Work Functionality, Social Functionality, and Energy/Vitality. Higher scores indicate better quality of life. The total score ranges from a minimum of 15 to a maximum of 105.
Outcome measures
| Measure |
Experimental Group
n=39 Participants
reflexology was applied to the experimental group
Reflexology: Reflexology is a practice based on the fact that the organs in the body are connected to the reflex areas in the hands and feet.
|
Control Group
n=39 Participants
reflexology was not applied to the control group
|
|---|---|---|
|
24-Hour Migraine-Specific Quality of Life Questionnaire (24 h MQoLQ)
|
81.05 Score (15-105)
Standard Deviation 8.97
|
69.51 Score (15-105)
Standard Deviation 8.99
|
Adverse Events
Experimental Group
Control Group
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Assistant Professor Cihat DEMİREL
Muş Alparslan University
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place